Methyl-CpG-binding domain proteins: readers of the epigenome

Q Du, PL Luu, C Stirzaker, SJ Clark - Epigenomics, 2015 - Taylor & Francis
protein binding requires both functional MBD domains and methyl-CpGs; however, some
MBD proteins … regulatory regions via alternative regulatory domains or interaction with the …

[HTML][HTML] Comparative study of methyl-CpG-binding domain proteins

TC Roloff, HH Ropers, UA Nuber - BMC genomics, 2003 - Springer
… In this study we present additional four proteins and two cDNAs with a methyl-CpG-binding
domain in mouse and man. Transcripts of SETDB1, BAZ2A, CLLL8, KIAA1461 and KIAA1887 …

Recognition of methylated DNA through methyl-CpG binding domain proteins

X Zou, W Ma, IA Solov'Yov, C Chipot… - Nucleic acids …, 2012 - academic.oup.com
… MBD proteins is still poorly understood. In this article, we demonstrate that the methyl-CpG
Through molecular dynamics and quantum-chemistry calculations we investigate the methyl

Biological functions of methyl-CpG-binding proteins

PA Defossez, I Stancheva - Progress in molecular biology and translational …, 2011 - Elsevier
… of methyl-CpG-binding proteins: the MBD protein family, Kaiso and Kaiso-like proteins, and
SRA domain proteins… We discuss the structural bases of methyl-CpG recognition, the function …

Methyl CpG‐binding proteins and transcriptional repression

PA Wade - Bioessays, 2001 - Wiley Online Library
… (7) The protein is chromatin associated(8) and localizes to densely … of the protein is devoted
to selective recognition of methyl CpG. It also contains a transcriptional repression domain (…

MethylCpG‐binding proteins: Targeting specific gene repression

E Ballestar, AP Wolffe - European journal of biochemistry, 2001 - Wiley Online Library
… to the density of methyl-CpGs may account for differences in … of CpG seem to have different
affinities for MBD proteins (our … around a CpG influences binding of an MBD protein. It is also …

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

PA Wade - Oncogene, 2001 - nature.com
… ), this review will focus instead on proteins that function downstream of the DNA methylation
… featuring DNA methylation, this review will focus on methyl CpG binding proteins in animals. …

The roles of the methyl-CpG binding proteins in cancer

L Parry, AR Clarke - Genes & cancer, 2011 - journals.sagepub.com
… for the maximal apoptotic effects of many of these chemotherapeutic drugs, 124,125 a role
that may in part be mediated through an interaction with Fas-associated death domain protein

The methyl-CpG binding domain and the evolving role of DNA methylation in animals

B Hendrich, S Tweedie - TRENDS in Genetics, 2003 - cell.com
… The number and variety of proteins containing methyl-CpG binding domains (MBDs) that
are encoded in animal genomes also varies, with a general correlation between the extent of …

[HTML][HTML] DNA methylation and methyl-CpG binding proteins: developmental requirements and function

O Bogdanović, GJC Veenstra - Chromosoma, 2009 - Springer
methyl-CpG binding domain proteins (MBDs) and several structurally unrelated methyl-CpG
binding zinc-finger proteins … These proteins generally are thought to associate with histone …