… MBD2 are involved in histone deacetylase-dependent repression and it is likely that this is …
histone deacetylases to methyl CpG-enriched regions in the genome to repress transcription. …

… animals result from alterations in patterns of gene expression. The lack of any molecular …
thusfar) to demonstrate any alterations in gene expression in the MeCP2 and MBD2 null animals…

… on genes with a low density of methyl-CpG. We found thatsparse methylation could repress
transfected genes … Densely methylated genes, however, could not be reactivated by the …

… In this study, the level of gene expression as a function of the degree of CpG methylation
was determined. Minichromosomes with four differentCpG densities, ie, 0% methylation, 7% …

… An important consequence of CpG methylation is the local silencing of gene expression.
In … for methyl-CpG. We have studied two proteins that bind to methylated DNA, methyl-CpG-…

… genes to their expression profiles, we determined the methyl-CpG configurations of the
promoters of five genes … stable methyl-CpG profiles associated with silencing or activation of the …

… To study the effect of CpG methylation on RNA polymerase I (pol I)-transcribed rRNA genes,
… to optimize pol I-driven reporter gene expression. Transfection of this plasmid into HepG2 (…

Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by
histone acetylation and methyl-CpG binding proteins | Molecular Cancer Therapeutics | …

… Here, by profiling discrete subtypes of neurons we uncovered more dramatic effects of
MeCP2 on gene expression, overcoming the “dilution problem” associated with assaying …

… and crucial for processes like imprinting, repression of gene activity and cancer. It has
been … methylated CpGs. The first reported member of this group of proteins is methyl-CpG-binding …