The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

F Fuks, PJ Hurd, D Wolf, X Nan, AP Bird… - Journal of Biological …, 2003 - ASBMB
… Here, we show that MeCP2 associates with histone methylation in vitro as well as in vivo.
The MeCP2-associated methylation activity is found to be specific for lysine 9 of histone H3. By …

Molecular coupling of DNA methylation and histone methylation

H Hashimoto, PM Vertino, X Cheng - Epigenomics, 2010 - Future Medicine
… the methyl-CpG-binding domain [MBD]) and the functional implications of domain architecture
in the mechanisms linking histone methylation and DNA methylation … the DNA methylation

[PDF][PDF] RETRACTED: Methyl-CpG Binding Protein MBD1 Couples Histone H3 Methylation at Lysine 9 by SETDB1 to DNA Replication and Chromatin Assembly

SA Sarraf, I Stancheva - Molecular cell, 2004 - cell.com
… Here we demonstrate in human cells that the methylmethylationCpG binding protein MBD1
associates with an H3 K9biological … was undetectable in our in vitro histone methylation In …

Structural and functional coordination of DNA and histone methylation

X Cheng - Cold Spring Harbor perspectives in biology, 2014 - cshperspectives.cshlp.org
… of DNA and its associated histones. This article … histone (arginine and lysine) methylation
and demethylation and functional links between the methylation status of the DNA and histones

DNA methylation pathways and their crosstalk with histone methylation

J Du, LM Johnson, SE Jacobsen… - Nature reviews Molecular …, 2015 - nature.com
histone methylation. We first discuss the CMT2–CMT3 pathway as it has the most direct link
to histone methylation. … DNMT3A-mediated methylation of a pair of CpG sites separated by …

Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins

RP Danam, SR Howell, TP Brent, LC Harris - Molecular cancer therapeutics, 2005 - AACR
… transformed cell lines is associated with methylated CpG hotspots in the MGMT 5′ … CpG
methylation of theMGMT promoter region influenced silencing of the gene. Analysis of histone

Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

N Fujita, S Watanabe, T Ichimura, S Tsuruzoe… - Journal of Biological …, 2003 - ASBMB
… Here we show that histone H3 methylase Suv39h1 and the methyl lysine-binding protein HP1
… complex and may tether it to methylated DNA regions for establishing histone methylation. …

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

PA Wade - Oncogene, 2001 - nature.com
… and histone modificationmethylation signal. While higher plants clearly possess sophisticated
gene regulatory circuits featuring DNA methylation, this review will focus on methyl CpG

Mechanisms of DNA methylation, methyl-CpG recognition, and demethylation in mammals

X Cheng, H Hashimoto, JR Horton, X Zhang - Handbook of epigenetics, 2011 - Elsevier
… We thank most warmly our colleagues and coworkers whose hard work was responsible
for much of the DNA and histone methylation work cited in this review. Work in the authors’ …

Linking DNA methylation and histone modification: patterns and paradigms

H Cedar, Y Bergman - Nature Reviews Genetics, 2009 - nature.com
… In animal cells, DNA can be modified by methylation of cytosine residues in CpG … how
histone modification and DNA methylation can have different roles in gene silencing, with histone