… repressors to methylated DNA. Two such factors, MeCP-1 and MeCP-2 (methyl cytosine
binding proteins 1 and 2), have been identified and shown to bind to methylated CpG residues …

… are occupied by various proteins, including methyl-CpG binding … of DNA methylation, DNA
methyltransferases, and methyl-CpG … DNA methylation makes an essential and versatile …

… MBD of human MBD1 in complex with methylated DNA. We also present mutational binding
… and DNA in the NMR structure. The structure explains how MBD can access exposed CpG …

… methyl-CpG binding domain (MBD) proteins play an important role in interpreting the genetic
information encoded by methylated DNA … that the methyl-CpG dinucleotides are recognized …

… , the methyl-CpG binding proteins could have facilitated the expansion of the methylated
DNA … We will review the function of methyl-CpG binding proteins in mammals, and point out …

… bind methylated DNA in solution.(37) It was distinct from MeCP2 in that it required a densely
methylated DNA fragment (11 or more methyl CpG … require multiple methyl CpG sites when …

… , we reasoned that any methylated DNA added to the in vitro transcription reaction should
be able to compete out the inhibitor and restore expression from the methylated gene. To test …

… the extent of methylation of the CpG sequence in eukaryotic DNA we have developed a
technique for measur~g the nearest neighbors of m’Cyt. mSCyt cannot be detected by the conven…

… to enrich for methylated DNA regions of the genome, namely methylDNA … methylated DNA
using a methyl-CpG binding domain-based (MBD) protein to discover differentially methylated …

… from densely methylated genes can be mediated by the methyl‐CpG binding protein MeCP‐…
of methylation on genes with a low density of methyl‐CpG. We found that sparse methylation …