Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1

N Fujita, N Shimotake, I Ohki, T Chiba… - … and cellular biology, 2000 - Am Soc Microbiol
… DNAs, and green fluorescent protein-fused MBD1 mutants did not localize properly in the …
that MBD1 acts as a transcriptional regulator depending on the density of methyl-CpG pairs …

[HTML][HTML] An epigenetic regulator: methyl-CpG-binding domain protein 1 (MBD1)

L Li, BF Chen, WY Chan - International journal of molecular sciences, 2015 - mdpi.com
MBD1 acts as an epigenetic regulator via different … the MCAF1/MBD1/SETDB1 complex or
the MBD1-HDAC3 complex… , MBD1 with its interacting partners, including proteins and non-…

The methyl-CpG binding protein MBD1 is required for PML-RARα function

R Villa, L Morey, VA Raker… - Proceedings of the …, 2006 - National Acad Sciences
… Here we report that MBD1, a member of a conserved family of proteins able to bind … MBD1
to its target promoter through an HDAC3-mediated mechanism. Binding of HDAC3 and MBD1

Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms

N Fujita, S Takebayashi, K Okumura… - … and cellular biology, 1999 - Taylor & Francis
… a human MBD1 protein, one of the components of MeCP1, which possesses a methyl-CpG
binding domain (MBD) and cysteine-rich (CXXC) domains. Four novel MBD1 isoforms (…

Methyl CpG‐binding proteins and transcriptional repression

PA Wade - Bioessays, 2001 - Wiley Online Library
… ascribed to cross reaction of MBD1 antisera with other MBD proteins unknown at the time.(…
multiple methyl CpG sites when MBD2 can selectively recognize a single methyl CpG in …

[HTML][HTML] Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA

I Ohki, N Shimotake, N Fujita, JG Jee, T Ikegami… - Cell, 2001 - cell.com
… In vertebrates, the biological consequences of DNA methylation are often mediated by protein
factors containing conserved methyl-CpG binding domains (MBDs). Mutations in the MBD …

Regulation of transcription and chromatin by methyl-CpG binding protein MBD1

M Nakao, S Matsui, S Yamamoto, K Okumura… - Brain and …, 2001 - Elsevier
… by specific protein factors that contain a highly conserved methyl-CpG binding … proteins:
MBD1, MBD2, MBD3, MBD4 and MeCP2. In the family of methyl-CpG binding proteins, MBD1 is …

[HTML][HTML] Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

N Fujita, S Watanabe, T Ichimura, S Tsuruzoe… - Journal of Biological …, 2003 - ASBMB
… and the methyl lysine-binding protein HP1 interact with MBD of MBD1. Suv39h1 enhances
MBD1-mediated transcriptional repression via MBD but not the C-terminal TRD of MBD1. …

[HTML][HTML] Comparative study of methyl-CpG-binding domain proteins

TC Roloff, HH Ropers, UA Nuber - BMC genomics, 2003 - Springer
… vertebrate MBD proteins have been identified as members of the MBD protein family: MBD1,
MBD2… by the recruitment of HDACs has been shown for MECP2, MBD1 and MBD2 [11–13]. …

[PDF][PDF] RETRACTED: Methyl-CpG Binding Protein MBD1 Couples Histone H3 Methylation at Lysine 9 by SETDB1 to DNA Replication and Chromatin Assembly

SA Sarraf, I Stancheva - Molecular cell, 2004 - cell.com
… of DNA replication machinery, to reconstitute symmetrically methylated CpGs genetic
modifications through DNA replication. Here we show that the methyl-CpG binding protein MBD1