Methyl-CpG binding proteins: specialized transcriptional repressors or structural components of chromatin?
T Clouaire, I Stancheva - Cellular and Molecular Life Sciences, 2008 - Springer
… the function of methyl-CpG binding proteins in transcriptional … Finally, we provide a brief
overview of how methyl-CpG … In this review we focus on the methyl-CpG binding proteins and …
overview of how methyl-CpG … In this review we focus on the methyl-CpG binding proteins and …
Methyl‐CpG‐binding proteins: Targeting specific gene repression
E Ballestar, AP Wolffe - European journal of biochemistry, 2001 - Wiley Online Library
… For instance, MeCP2 has the character of a structural component of the chromosome that
ensures long-term silencing of methylated sequences. MBD2/MeCP1, on the other hand, is …
ensures long-term silencing of methylated sequences. MBD2/MeCP1, on the other hand, is …
Methyl CpG binding proteins: coupling chromatin architecture to gene regulation
PA Wade - Oncogene, 2001 - nature.com
… , this review will focus on methyl CpG binding proteins in animals. … It might also result in
structural effects on nucleosomes … Secondary structures as predicted from the structures of …
structural effects on nucleosomes … Secondary structures as predicted from the structures of …
[HTML][HTML] Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA
… methyl-CpG binding domains (MBDs). Mutations in the MBD protein MeCP2 cause the
neurodevelopmental disease Rett syndrome. We report here the solution structure … of the methyl …
neurodevelopmental disease Rett syndrome. We report here the solution structure … of the methyl …
Biological functions of methyl-CpG-binding proteins
PA Defossez, I Stancheva - Progress in molecular biology and translational …, 2011 - Elsevier
… methyl-CpG-binding proteins: the MBD protein family, Kaiso and Kaiso-like proteins, and SRA
domain proteins. We discuss the structural bases of methyl-CpG … which are components of …
domain proteins. We discuss the structural bases of methyl-CpG … which are components of …
[HTML][HTML] Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1
I Ohki, N Shimotake, N Fujita, M Nakao… - The EMBO …, 1999 - embopress.org
… methylation in vertebrates is important for gene silencing, alterations in chromatin structure
… shared methyl-CpG-binding domains (MBDs). We have determined the solution structure of …
… shared methyl-CpG-binding domains (MBDs). We have determined the solution structure of …
Recognition of methylated DNA through methyl-CpG binding domain proteins
… structures, namely MBD1–mDNA, MBD2–mDNA and MeCP2–mDNA, to examine the mechanism
of methyl-CpG … the energies of its individual components, corresponding to the energy …
of methyl-CpG … the energies of its individual components, corresponding to the energy …
[HTML][HTML] CpG methylation, chromatin structure and gene silencing—a three-way connection
A Razin - The EMBO journal, 1998 - embopress.org
… structure has been known for almost two decades. Nevertheless, the molecular link between
methyl … produced depicting chromatin structure as a major component in determining the …
methyl … produced depicting chromatin structure as a major component in determining the …
Mechanisms of DNA methylation, methyl-CpG recognition, and demethylation in mammals
X Cheng, H Hashimoto, JR Horton, X Zhang - Handbook of epigenetics, 2011 - Elsevier
… This chapter summarizes the recent structural and biochemical advances in … components
(histones and DNA) carrying appropriate markers (on the tails of H3 and hemimethylated CpG …
(histones and DNA) carrying appropriate markers (on the tails of H3 and hemimethylated CpG …
Methyl CpG‐binding proteins and transcriptional repression
PA Wade - Bioessays, 2001 - Wiley Online Library
… methyl CpG dinucleotide.(7) The assignment of key residues within the MeCP2 MBD as crucial
for either structural … 400 kDa suggesting it may be a component of a multiprotein complex.(…
for either structural … 400 kDa suggesting it may be a component of a multiprotein complex.(…
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