[HTML][HTML] CpG methylation changes G-quadruplex structures derived from gene promoters and interaction with VEGF and SP1
… that CpG methylation of DNA within G4 structures caused … of structures with differing
topology, multimer components, or … Moreover, hydrophobic methyl groups on cytosine affect the …
topology, multimer components, or … Moreover, hydrophobic methyl groups on cytosine affect the …
[HTML][HTML] Knock-down of methyl CpG-binding protein 2 (MeCP2) causes alterations in cell proliferation and nuclear lamins expression in mammalian cells
F Babbio, I Castiglioni, C Cassina, MB Gariboldi… - BMC cell biology, 2012 - Springer
… Our results that indicate reduced levels of NE components, are … The major components of
the lamina are intermediate … and fundamental components for nuclear structure and nuclear …
the lamina are intermediate … and fundamental components for nuclear structure and nuclear …
[HTML][HTML] Specific Methyl-CpG configurations define cell identity through gene expression regulation
T Improda, V Morgera, M Vitale, L Chiariotti… - International Journal of …, 2023 - mdpi.com
… profiles, we determined the methyl-CpG configurations of the … the structure of significant,
dynamic, and stable methyl-CpG … , in which each core component is identified by the CpGs (105–…
dynamic, and stable methyl-CpG … , in which each core component is identified by the CpGs (105–…
Molecular coupling of DNA methylation and histone methylation
H Hashimoto, PM Vertino, X Cheng - Epigenomics, 2010 - Taylor & Francis
… Finally, we consider the domain structure of the DNA … structures of MeCP2 and MBD1 in
complex with methyl-CpG … of direct interaction with chromatin components in addition to DNA. …
complex with methyl-CpG … of direct interaction with chromatin components in addition to DNA. …
Crystal structure of the mismatch-specific thymine glycosylase domain of human methyl-CpG-binding protein MBD4
W Zhang, Z Liu, L Crombet, MF Amaya, Y Liu… - Biochemical and …, 2011 - Elsevier
… It contains an amino-proximal methyl-CpG binding domain (MBD) and a C-terminal … the
crystal structure of C-terminal glycosylase domain of human MBD4. And the structural alignments …
crystal structure of C-terminal glycosylase domain of human MBD4. And the structural alignments …
CpG dinucleotide positioning patterns determine the binding affinity of methyl-binding domain to nucleosomes
… The methyl-binding domain of MBD1 is a common methyl CpG binding motif and has been
… The structure of MBD1-DNA complex suggests that the methyl-binding domain of MBD1 …
… The structure of MBD1-DNA complex suggests that the methyl-binding domain of MBD1 …
Methyl‐CpG binding domain (MBD) 2/3 specifically recognizes and binds to the genomic mCpG site with a β‐sheet in the MBD to affect embryonic development in …
TY Fu, SS Ji, YL Tian, YG Lin, YM Chen… - Insect …, 2023 - Wiley Online Library
… The methyl-CpG in the major groove is in contact with … and Ser-45, as determined by structural
analysis of the MBD–mCpG … which secondary structures can affect the β-sheet structure in …
analysis of the MBD–mCpG … which secondary structures can affect the β-sheet structure in …
Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2
… methyl CpG-binding protein 2 (MeCP2), and discuss how differential binding affinity of MeCP2
for non-CpG and … Indeed, it now is recognized that several structurally unrelated protein …
for non-CpG and … Indeed, it now is recognized that several structurally unrelated protein …
Human thymine DNA glycosylase (TDG) and methyl‐CpG‐binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg: G mispair
JH Yoon, S Iwai, TR O'Connor… - Nucleic acids …, 2003 - academic.oup.com
… Several proteins binding to methylated CpG sites have been identified, MeCP2 and a group
… a conserved methyl‐CpG‐binding domain (MBD) domain ( 15 ). One of these methyl‐CpG‐…
… a conserved methyl‐CpG‐binding domain (MBD) domain ( 15 ). One of these methyl‐CpG‐…
The dinucleotide CG as a genomic signalling module
A Bird - Journal of molecular biology, 2011 - Elsevier
… proteins that modulate chromatin structure. Non-methylated … G residues within the methyl-CpG
dinucleotide, confirming the … We need to know all the molecular components relating to the …
dinucleotide, confirming the … We need to know all the molecular components relating to the …