… relationship exists between DNA methylation and transcription … of targeted tools for
manipulating DNA methylation offers the … of DNA methylation in the mammalian genome and …

… We all start life thanks to inhibition of DNA methylation. As soon as embryogenesis begins,
a massive decrease in DNA methylation reprograms the epigenome and creates a nearly …

… Here we show that in vitro-methylated DNA can be efficiently targeted into defined genomic
… Consistent with the model of HDAC recruitment by methylated DNA (Citation1), we observe …

… genomic binding for the MBD protein family and selected variants, we employed a
recombinase-mediated, genomic targeting … of interest from a single defined genomic site. This …

… We cloned a methylated DNA binding protein that was also cloned by Adrian Bird’s group
and was termed MBD2 (Hendrich and Bird, 1998). We showed that a shorter isoform of the …

… of DNA methylation and other … DNA methylation an excellent target for anticancer therapies.
During the last few decades, an increasing number of drugs targeting DNA methylation have …

… DNA methylation is targeted to specific regions of the genome and interpreted by methyl-CpG…
Recent studies have illuminated the role of DNA methylation in controlling gene expression …

… directed to the specific target sites by the DBDs, such that DNA methylation only occurs in
the vicinity of these target sites. We here report targeted DNA methylation as well as efficient …

… DNA methylation and transcription. Here, we focus on recent advances in targeted DNA
methylation … they have provided into how forcible methylation and demethylation govern gene …

… DNA methylation, we designed a probe set to target ∼10,000 locations in bisulfite-treated
human genomic DNA (… , probes were designed to target 10-nucleotide regions containing at …