Impact of methylation on the physical properties of DNA

A Pérez, CL Castellazzi, F Battistini, K Collinet… - Biophysical journal, 2012 - cell.com
… in regulatory possibilities offered by methylation. Indeed, highly methylated DNA is typically
associated with inactive genes, whereas methylation depletion is observed for active genes ( …

Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation

D Schübeler, MC Lorincz, DM Cimbora… - … and cellular biology, 2000 - Am Soc Microbiol
… Here we show that in vitro-methylated DNA can be efficiently targeted into defined genomic
… of methylation-induced repression, as well as the dynamics of the methylation pattern, we …

The impact of metabolism on DNA methylation

CL Ulrey, L Liu, LG Andrews… - Human molecular …, 2005 - academic.oup.com
… Nutrition and metabolism are the sources of methyl groups that are used to methylate
DNA, a process that influences chromatin structure and gene expression. In so far as a …

How does DNA methylation repress transcription?

SU Kass, D Pruss, AP Wolffe - Trends in Genetics, 1997 - cell.com
DNA methylation influences chromatin function … dependent on methylated DNA that can be
explained by methylation-… influence DNA methylation and gene expression in dividing cells, …

DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… parental DNA stand retains the original DNA methylation pattern (… the original DNA methylation
pattern by adding methyl groups (red) … influence between miRNA and DNA methylation. …

DNA methylation affects the formation of active chromatin

I Keshet, J Lieman-Hurwitz, H Cedar - Cell, 1986 - cell.com
… The fact that the methyl group can indeed influence the affinity of specific proteins at their …
ladder on methylated DNA, we still consider it likely that DNA methylation may also have subtle …

[HTML][HTML] New findings showing how DNA methylation influences diseases

F Sallustio, L Gesualdo, A Gallone - World Journal of Biological …, 2019 - ncbi.nlm.nih.gov
… For example, 99.98% of the methylated DNA regions in normal cells, such as fibroblasts, are
rich in C and G, whereas the methylation in stem cells is concentrated in sequences that are …

DNA methylation

MG Marinus, A Løbner-Olesen - EcoSal Plus, 2014 - Am Soc Microbiol
… only if the sequence is methylated; Sau3A cuts regardless of the state of methylation. EcoRII
Methylation of GATC sites can influence DNA structure because the methyl group protrudes …

Methylation of cytosine influences the DNA structure

W Zacharias - DNA methylation: Molecular biology and biological …, 1993 - Springer
… -dA) and its cytosine-methylated analog revealed that the methylated polymer can form a
triple-… The stabilizing effect of cytosine methylation on triple-stranded DNA segments has also …

Effect of regional DNA methylation on gene expression.

I Keshet, J Yisraeli, H Cedar - Proceedings of the National …, 1985 - National Acad Sciences
influenced by DNA modification. To this end, we have prepared hybrid molecules, methylated
ei… tory suggest that methylated DNA inserted into animal cells in culture by DNA-mediated …