Active repression of methylated genes by the chromosomal protein MBD1
HH Ng, P Jeppesen, A Bird - Molecular and cellular biology, 2000 - Taylor & Francis
… A previous study showed that MBD1 is able to repress transcription of a methylated gene in
… We show that MBD1 can actively repress methylated genes in vivo via a powerful repression …
… We show that MBD1 can actively repress methylated genes in vivo via a powerful repression …
DNA methylation: the nuts and bolts of repression
TB Miranda, PA Jones - Journal of cellular physiology, 2007 - Wiley Online Library
… if DNA methylation really plays a … methylation in the silencing of germline specific genes
(Weber et al., 2007). By looking at global DNA methylation, this study found a subset of genes …
(Weber et al., 2007). By looking at global DNA methylation, this study found a subset of genes …
How does DNA methylation repress transcription?
… until successive cell divisions eventually unravel the repressive chromatin structure.
Although we focus on molecular mechanisms that might influence DNA methylation and gene …
Although we focus on molecular mechanisms that might influence DNA methylation and gene …
DNA methylation and silencing of gene expression
J Newell-Price, AJL Clark, P King - Trends in Endocrinology & Metabolism, 2000 - cell.com
… These data underscored the importance of MeCP2 for development and in mediating some
of the repressive effects of methylation, but suggested that other MBDs are also likely to play …
of the repressive effects of methylation, but suggested that other MBDs are also likely to play …
Role of DNA methylation in stable gene repression
L Lande-Diner, J Zhang, I Ben-Porath… - Journal of Biological …, 2007 - ASBMB
… DNA methylation on both gene expression and chromatin structure. Our results confirm that
the underlying methylation … that many methylated genes are subject to additional repression …
the underlying methylation … that many methylated genes are subject to additional repression …
DNA methylation directs a time-dependent repression of transcription initiation
SU Kass, N Landsberger, AP Wolffe - Current biology, 1997 - cell.com
… ) thymidine kinase (tk) gene after injection into rodent cells … methylation-dependent repression
of gene activity. Here, we examine the mechanism of methylation-dependent HSV tk gene …
of gene activity. Here, we examine the mechanism of methylation-dependent HSV tk gene …
Dependence of transcriptional repression on CpG methylation density
CL Hsieh - Molecular and cellular biology, 1994 - Am Soc Microbiol
… repression is a graded but exponential function of the CpG methylation density such that low
levels of methylation … CpG methylation is also an important regulator of gene expression in …
levels of methylation … CpG methylation is also an important regulator of gene expression in …
Brain feminization requires active repression of masculinization via DNA methylation
… The marked decrease in fully methylated CpGs following … fully methylated CpGs in the female
POA serve to repress gene … subset of genes to be methylation-dependent gene candidates …
POA serve to repress gene … subset of genes to be methylation-dependent gene candidates …
The role of epigenetic transcription repression and DNA methyltransferases in cancer
FI Daniel, K Cherubini, LS Yurgel, MAZ de Figueiredo… - Cancer, 2011 - Wiley Online Library
… of lysine 9 in the core histone H3 is associated with silenced genes,70 whereas methylation
of lysine 4 in histone H3 is a feature of active genes.22 DNA methylation and histone …
of lysine 4 in histone H3 is a feature of active genes.22 DNA methylation and histone …
[PDF][PDF] Mechanisms of transcriptional repression by histone lysine methylation
P Hublitz, M Albert, A Hfmpeters… - International Journal of …, 2009 - researchgate.net
… methylation mediated repression, and describe the functional interplay with activating H3K4
methylation. … outcomes from stable repression to highly dynamic regulated genes, strongly …
methylation. … outcomes from stable repression to highly dynamic regulated genes, strongly …
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