… methylation is graded versus all or none. That is, does the methylated state correlate with
transcriptional repression in … HSV tk promoter site becomes demethylated in the 7%methylated …

… We mainly focus on the dynamics of activating H3K4 and repressive H3K27 methylation
marks at promoter sequences. The genomic data serve as a foundation to understand the …

… mechanisms that might lead to transcriptional repression at methylated loci. Certain … (34)
In contrast, a recent biochemical analysis of MBD occupancy on a methylated promoter in the …

… Our findings suggest that MBD1 directly prevents transcription from methylated promoters
in a histone deacetylation-independent manner, through interacting with MCAF. …

… genes with methylated promoters did not seem to be affected by the lack of Dnmt1 in these
analyses, giving the impression that DNA methylation may not play a role in their repression. …

… transcriptional repression on unmethylated promoters in cis 6-39. This observation is consistent
with MeCP2 containing DNA-binding and transcriptional repression … binding to promoter …

… The experiments implicating MeCP-1 in transcriptional repression involved promoters
that are rich in methyl-CpG. The known preference of MeCP-1 for multiple methyl-CpGs on a …

… that HPVOPSCC have higher levels of gene promoter methylation compared with HPV-negative …
of transcriptional repression from DNA methylation at conventional promoter regions in …

… , methylated DNA is associated with transcriptional repression … of MeCP2 as a transcriptional
repressor in chromatin as a two-… transcription in vitro and in vivo from methylated promoters …

… methylation in tumorigenesis have been proposed. First, weakening of transcriptional repression
… According to the Knudson 2-hit hypothesis, promoter methylation may occur on a gene …