… -wide methylation in glioblastoma multiforme (GBM). Our goals were to study differential
methylation … global methylation markers. The discovery sample set for this study consisted of 54 …

… Our meta-analysis focuses on MGMT promoter methylation in patients with GBM. Although
the findings of two studies [21, 37] which reported the status of MGMT promoter methylation …

… and methylated status in GBM, we establish a signature for prognostication. A total of 3365
genes (2940 hypo-methylated and high-expressed genes; 425 hyper-methylated and low-…

… This study provides the first genome-wide integrative analysis of DNA methylation and gene
… analysis of DNA methylation and gene expression profiles obtained from the same GBM …

… In the present analysis, we have quantified the DNA methylation level of 1,505 CpG
dinucleotides (807 genes) in 87 consecutive GBMs using universal BeadArrays. Supervised cluster …

… Cluster analysis of differentially methylated genes between patients with glioblastoma
multiforme and controls. Each row represents a single gene and each column represents a single …

… of MGMT methylation as a biomarker for prognosis in GBM patients, the techniques to analyze
it … Prognostic value of three different methods of MGMT promoter methylation analysis in a …

… Whole-genome methylation analysis of glioblastomas has allowed a narrower classification
of tumor subtypes on the basis of the different methylome profiles. The epigenetic …

… methylation analysis have allowed establishing the methylome of large series of patient
samples. Pattern analysis … cancer [19, 21, 42] and more recently also glioma (G-CIMP) [29, 43, 45…

… We compared three different assays for MGMT promoter methylation analysis and included
MSP as a qualitative and potentially semi-quantitative, PSQ as a quantitative and MS-MLPA …