… of CpG methylation. I find that the repression is a graded but exponential function of the
CpG methylation density such that low levels of methylation yield a 67 to 90%o inhibition of …

… The experiments implicating MeCP-1 in transcriptional repression involved promoters
that are rich in methyl-CpG. The known preference of MeCP-1 for multiple methyl-CpGs on a …

… We summarize recent data that indicate a close relationship between GC density of promoter
sequences, transcription factor binding and the antagonizing activities of distinct epigenetic …

… in methylation-mediated repression. Analyses of histone acetylation in in vitro-methylated …
among de novo DNA methylation, transcriptional repression, and histone acetylation state. To …

… the degree of gene repression by MeCP2 is proportional to the total number of methylated
cytosine … Previously we have observed that both gene-body mCA density and gene length are …

… DNA that can be explained by methylation-specific re… Transcriptional repression is strongly
related to the density of … at low densities of methyl-CpG and repression at higher densities. …

… increasing density of methylation, but whether density itself … have higher levels of gene
promoter methylation compared with HPV-… of transcriptional repression from DNA methylation at …

… mechanisms that might lead to transcriptional repression at methylated loci. Certain … for
methylation density, of full-length MeCP2 from any species. Transcriptional repression mediated …

… CpG island density in promoter sequences predict transcriptional permissiveness of DNA …
transcriptionally repressive from permissive DNA methylation peaks in promoter gene …

… MeCP2 repress transcription in vitro from methylated promoters but do not … Repression is
nonlinearly dependent on the local density of methylation, becoming significant at the density …