Novel methylation panel for the early detection of colorectal tumors in stool DNA
D Azuara, F Rodriguez-Moranta, J de Oca… - Clinical colorectal …, 2010 - Elsevier
… This study aimed to assess the clinical usefulness of a panel of methylation biomarkers in
stool DNA in the identification of colorectal tumors, using methylation-specific melting curve …
stool DNA in the identification of colorectal tumors, using methylation-specific melting curve …
Stool DNA testing for the detection of pancreatic cancer: assessment of methylation marker candidates
… The primary approach to combining the individual DNA markers into a panel was stepwise
logistic regression with a probability to enter the model of 0.1 and a probability to leave of 0.05…
logistic regression with a probability to enter the model of 0.1 and a probability to leave of 0.05…
Performance evaluation of stool DNA methylation tests in colorectal cancer screening: a systematic review and meta‐analysis
M Gachabayov, E Lebovics, A Rojas… - Colorectal …, 2021 - Wiley Online Library
… evidence about whether stool DNA methylation tests allow … of stool DNA methylation tests
in detecting colorectal cancer. … is a panel including DNA methylation (NDRG4, BMP3), DNA …
in detecting colorectal cancer. … is a panel including DNA methylation (NDRG4, BMP3), DNA …
[HTML][HTML] DNA methylation markers detected in blood, stool, urine, and tissue in colorectal cancer: a systematic review of paired samples
EA Laugsand, SS Brenne, F Skorpen - International Journal of Colorectal …, 2021 - Springer
… We also identified one promising plasma panel and two stool panels. The correspondence
of methylation status was evaluated as very good for four markers, but only marginal for most …
of methylation status was evaluated as very good for four markers, but only marginal for most …
Analysis of DNA methylation at specific loci in stool samples detects colorectal cancer and high-grade dysplasia in patients with inflammatory bowel disease
JB Kisiel, P Klepp, HT Allawi, WR Taylor… - Clinical …, 2019 - Elsevier
… We hypothesized that an sDNA panel comprising well-selected methylated DNA markers
would show high sensitivity for IBD-associated CRC+HGD and maintain high specificity across …
would show high sensitivity for IBD-associated CRC+HGD and maintain high specificity across …
[HTML][HTML] The importance of stool DNA methylation in colorectal cancer diagnosis: A meta-analysis
… In the current study, single-gene stool DNA methylation analysis had a sensitivity (specificity)
for CRC and adenoma of 56.5% (93.2%) and 32.6% (93.2%), respectively. These statistics …
for CRC and adenoma of 56.5% (93.2%) and 32.6% (93.2%), respectively. These statistics …
[HTML][HTML] Stool DNA methylation assays in colorectal cancer screening
T Kadiyska, A Nossikoff - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
… Recently, a multitarget stool DNA test consisting of molecular assays for aberrantly methylated
… Moreover, further DNA stool test panels are likely to become commercially available in the …
… Moreover, further DNA stool test panels are likely to become commercially available in the …
Analysis of fecal DNA methylation to detect gastrointestinal neoplasia
T Nagasaka, N Tanaka, HM Cullings… - JNCI: Journal of the …, 2009 - academic.oup.com
… in stool samples from diseased patients. One or more methylation markers was detected in
fecal DNA … For each of three patients' samples, the panels show the detection of methylation …
fecal DNA … For each of three patients' samples, the panels show the detection of methylation …
Methylation changes in faecal DNA: a marker for colorectal cancer screening?
HM Müller, M Oberwalder, H Fiegl, M Morandell… - The Lancet, 2004 - thelancet.com
… whether methylation changes in faecal DNA isolated from stool … DNA from stool samples
was isolated by means of the … Sensitivity and specificity of a stool DNA multitarget assay panel …
was isolated by means of the … Sensitivity and specificity of a stool DNA multitarget assay panel …
Analytical sensitivity and stability of DNA methylation testing in stool samples for colorectal cancer detection
LJW Bosch, S Mongera, JST sive Droste, FA Oort… - Cellular oncology, 2012 - Springer
… Amplification of human DNA by ß-globin PCR (upper panel) … of a stool DNA methylation
assay on partial stool samples … degradation of DNA methylation when stool samples were left at …
assay on partial stool samples … degradation of DNA methylation when stool samples were left at …
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