DNA methylation in genomic imprinting, development, and disease

M Paulsen, AC Ferguson‐Smith - The Journal of pathology, 2001 - Wiley Online Library
… in imprinting in mammals is the methylation of CpGs. Imprinted genes are characterized by
methylation patterns … The best-characterized imprinted genes in human and mouse so far are …

Newborns of obese parents have altered DNA methylation patterns at imprinted genes

A Soubry, SK Murphy, F Wang, Z Huang… - International journal of …, 2015 - nature.com
… To determine the independent effects of preconceptional maternal or paternal obesity on
offspring DNA methylation at the seven DMRs of the imprinted genes studied, we controlled for …

Regulation of imprinted DNA methylation

R Holmes, PD Soloway - Cytogenetic and genome research, 2006 - karger.com
… prevented establishment of normally methylated maternal imprint marks and in male PCGs
a number of normally methylated paternal imprinted genes were unmethylated, with the …

[PDF][PDF] Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm

C Stouder, A Paoloni-Giacobino - Reproduction, 2010 - scholar.archive.org
… Therefore, it is quite possible that small changes in the methylation pattern of imprinted
genes, such as those described in this study, might have biological consequences. …

Methylation dynamics of imprinted genes in mouse germ cells

D Lucifero, C Mertineit, HJ Clarke, TH Bestor… - Genomics, 2002 - Elsevier
methylation imprints are established have not been well defined. In this study, we used bisulfite
sequencing to determine the methylation dynamics of the imprinted genesgene 3 (Peg3)…

The ontogeny of allele‐specific methylation associated with imprinted genes in the mouse.

M Brandeis, T Kafri, M Ariel, JR Chaillet… - The EMBO …, 1993 - embopress.org
imprinting, we have analysed the methylation patterns of the endogenous imprinted genes
… clearly associated with regions of allele-specific methylation. By means of a highly sensitive …

Abnormal methylation of imprinted genes in human sperm is associated with oligozoospermia

CJ Marques, P Costa, B Vaz, F Carvalho… - MHR-Basic Science …, 2008 - academic.oup.com
… Genomic imprinting marks in the male germ line are already … the methylation patterns of H19
and MEST imprinted genes in … defective methylation of H19 and/or MEST imprinted genes. …

Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues

N Pervjakova, S Kasela, AP Morris, M Kals… - …, 2016 - Taylor & Francis
… monoallelic gene expression. The aim of this study was to compare the … methylation status
of imprinted genes and imprinting control regions (ICRs), harboring differentially methylated

Superovulation in mice alters the methylation pattern of imprinted genes in the sperm of the offspring

C Stouder, S Deutsch, A Paoloni-Giacobino - Reproductive Toxicology, 2009 - Elsevier
methylation patterns of imprinted genes are restricted to male germline cells, the methylation
patterns of our 5 target genes … As observed in the tail, the amount of methylated CpGs was …

Role of DNA methylation in imprinting disorders: an updated review

AR Elhamamsy - Journal of Assisted Reproduction and Genetics, 2017 - Springer
imprinted genes in mice and around 94 imprinted genes in human have been reported and
identified [11, 12]. Most of these imprinted genesmethylated region (DMR). DMRs in most …