… reprogramming events may have important implications for the efficiency of epigenetic
reprogramming that … on species-specific aspects of preimplantation DNA methylation dynamics. …

… Indeed, reprogramming results in a general decrease in subtelomeric DNA methylation. …
between iPS cell clones and even between different chromosomes in the same clone [39]. …

… Identifying the specific effects of aberrant methylation, as it relates to transcriptional
reprogramming is necessary to fully understand how incorrect genomic remodeling can interfere with …

… It is manifested by high mutation frequencies driven by changes in nucleic acid sequences,
chromosome rearrangement, or aneuploidy. In close association with these genetic events is …

… , including aberrant methylation and abnormal imprinted gene … can be reprogrammed during
the cloning process, successful … Our data indicate that this may be due in part to aneuploidy/…

… Global epigenetic reprogramming is considered to be … polar body extruded and the
chromosomes which start to decondense, (2… H3K9 methylation directed the de novo DNA …

… a single active X chromosome, since in aneuploid individuals possessing more than two X
… pre-existing patterns of methylation in germ-line reprogramming. This latter process could …

… methylation in human X aneuploidy cells. … X aneuploidy cells (45,X and 47,XXX) as a model
system, we have investigated the effect of altered chromosomal number on DNA methylation…

… have successfully reprogrammed somatic cells from aneuploid … (C) DNA methylation analysis
of OCT4 and NANOG … method, but we cannot discard that the X chromosome imbalance …

… derived by factor-based reprogramming from different tissues [43, 44]; as it was shown that
… and epigenetic changes associated with aneuploidies (Fig. 2). On autosomes, male, female, …