… II pathways have provided new insights into the biology of antigen presentation 4 ; however,
… , MHC class I antigen presentation is discussed, followed by MHC class II presentation. We …

… Abstract: MHC class I antigen presentation refers to the co-ordinated activities of … of MHC
class I/β 2 m heterodimers loaded with a spectrum of self or foreign peptides. These MHC class …

… MHC class I genes in mammalian species varies from 6 to over 1000 (38). High polymorphism
is confined to one to three "classical"(class la) genes that function in antigen presentation …

… repertoire that is presented on the surface by MHC class I or MHC class II proteins for CD8+
… MHC binding groove is an important, but certainly not the sole determinant of its presentation…

… MHC I molecules are not essential for cell survival and … control is by losing MHC I antigen
presentation machinery (APM). … evidence that loss of MHC I antigen presentation is a frequent …

… is the defining function of antigen-presenting cells (APC) as … MHC class II-restricted antigen
presentation to CD4 T cells is … protein antigens and the site of peptide binding to MHC class II …

… In this Review, we discuss how viral inhibitors target the MHC class I antigen presentation
pathway and the relevance of characterizing these mechanisms for increasing our …

… of antigen presentation by MHC II is of crucial importance to identify these factors or reveal
modes for controlling MHC II antigen presentation. … of regulating MHC II antigen presentation. …

… presented by MHC class I molecules. The current model of the pathway for antigen presentation
by MHC class I … onto the MHC class I molecules. The proteasome has been implicated in …

… interfere with antigen presentation by major histocompatibility complex (MHC) class I
molecules. These viruses utilize a whole variety of ingenious strategies to inhibit the MHC class I …