MicroRNA dysregulation in Alzheimer's disease

M Putteeraj, YM Fairuz, SL Teoh - … & Neurological Disorders …, 2017 - ingentaconnect.com
… regulators of many neurodegenerative diseases, including AD. We reviewed recent studies
identifying various miRNA dysregulated in AD. These miRNAs could play a significant role in …

Dysregulated miRNAs in progression and pathogenesis of Alzheimer's disease

T Arora, V Prashar, R Singh, TS Barwal… - Molecular …, 2022 - Springer
… red dots are for Alzheimer disease, green dots are for cancer, yellow depicts involvement in
cell cycle, and cyan for long-term potentiation. These highly dysregulated miRNAs are highly …

MicroRNAs in Alzheimer's disease

C Delay, W Mandemakers, SS Hébert - Neurobiology of disease, 2012 - Elsevier
miRNA target sites located within the 3′untranslated regions (3′UTRs) of APP and BACE1
genes. Here, we review current findings regarding miRNAmiRNAs to AD pathophysiology. …

Epigenetically regulated microRNAs in Alzheimer's disease

DL Van den Hove, K Kompotis, R Lardenoije… - Neurobiology of …, 2014 - Elsevier
… So far, results from miRNA profiling experiments in postmortem brain tissue suggest that
a number of specific miRNAs are dysregulated in patients with AD, several of which regulate …

Dysregulation and diagnostic potential of microRNA in Alzheimer's disease

Y Pan, R Liu, E Terpstra, Y Wang… - … of Alzheimer's …, 2016 - content.iospress.com
… It seems that the miRNA network in AD is tightly regulated by feedback loops, Aβ production
may lead to miRNA dysregulation, which in turn can affects AβPP mRNA levels and Aβ …

The potential role of dysregulated miRNAs in Alzheimer's disease pathogenesis and progression

AA Patel, GAP Ganepola, JR Rutledge… - … Alzheimer's Disease, 2019 - content.iospress.com
… of AD in the form of dysregulation of miRNA function, and especially on its effect on the three
hallmarks of AD. As discussed in detail, we have observed that many miRNA species play …

The role of microRNAs in Alzheimer's disease and their therapeutic potentials

M Miya Shaik, IA Tamargo, MB Abubakar, MA Kamal… - Genes, 2018 - mdpi.com
… Some of the miRNAs found to be dysregulated in AD have … pathogenic functions of several
dysregulated miRNAs in AD, … As the National Institute on Aging and Alzheimer Association’…

Deciphering the function and regulation of microRNAs in Alzheimer's disease and Parkinson's disease

L Qiu, W Zhang, EK Tan, L Zeng - ACS chemical neuroscience, 2014 - ACS Publications
diseases remain largely unknown. Here, we review the evidence for the functional role of
dysregulated miRNAs involved in disease pathogenesis, as well as how miRNAs govern …

Dysregulated microRNAs in neurodegenerative disorders

P Lau, B de Strooper - Seminars in cell & developmental biology, 2010 - Elsevier
Dysregulation of such miRNAs may contribute to up-regulation of APP and BACE1, leading
to accumulation of plaques and tangles in Alzheimer's disease. Dysregulated miRNAs in AD …

Brain microRNAs dysregulation: Implication for missplicing and abnormal post-translational modifications of tau protein in Alzheimer's disease and related tauopathies

M Bazrgar, P Khodabakhsh, F Mohagheghi… - Pharmacological …, 2020 - Elsevier
miRNA dysregulation may be helpful for subsequent therapeutic development. This article
reviews studies focused on the presently known roles of miRNAs in … dysregulated miRNAs in …