Midazolam for premedication in children: nasal vs. rectal administration

C Lejus, M Renaudin, S Testa… - European journal of …, 1997 - Wiley Online Library
… to that following rectal and nasal administration of midazolam (MDZ) rectal administration
with a shorter delay of onset. for premedication. Ninety-five ASA I and II paediatric Nasal …

Premedication with midazolam in children. Effect of intranasal, rectal and oral routes on plasma midazolam concentrations

JM Malinovsky, C Populaire, A Cozian… - …, 1995 - Wiley Online Library
… , oral and rectal administration of midazolam induced sedation in a similar time, but intranasal
administration in … This route of administration seems to be an excellent alternative for rapid …

Premedication with midazolam in young children: a comparison of four routes of administration

A Kogan, J Katz, R Efrat, LA Eidelman - Pediatric Anesthesia, 2002 - Wiley Online Library
administration of midazolam via a ‘noninvasive route’ is generally pain free, it might be
associated with minor side-effects. Rectal midazolam administration … Oral and rectal midazolam

Plasma concentrations of midazolam after iv, nasal or rectal administration in children

JM Malinovsky, C Lejus, F Servin… - BJA: British Journal …, 1993 - academic.oup.com
… Saint-Maurice and colleagues studied rectal midazolam 0.3 mg kg"1 premedication in 16
children, but pharmacokinetic data were obtained in only nine, and there was no comparison …

Comparison of Intranasal, Oral, and Rectal Midazolam for Premedication in Children.

C Chung, GB Hwang, KH Yea, SI Lee - Korean Journal of Anesthesiology, 1998 - ekja.org
… of crying at the drug administration and rapid onset and recovery. In overall age, rectal route
was better because of … This study suggests that administration route should be considered …

The use of midazolam in premedication

SGE Lindahl - Acta anaesthesiologica scandinavica, 1990 - Wiley Online Library
… tion (12) and is 0.3 for rectal administration (13), whereas … midazolam were reached at
an average of 16 min after rectal … The pharmacokinetics of rectal midazolam for premedication

Rectal administration of midazolam versus diazepam for preanesthetic sedation in children.

R Holm-Knudsen, TG Clausen, D Enà- Anesthesia Progress, 1990 - ncbi.nlm.nih.gov
dose was 7 ml (midazolam 14 mg, diazepam 26.25 mg). The premedication was administered
by a ward nurse 30 min before the expected induction ofanesthesia through a rectal

Paradoxical reactions to rectal midazolam as premedication in children

JA Roelofse, DH Stegmann, J Hartshore… - International journal of …, 1990 - Elsevier
… It is clear from the results obtained in this study that rectal midazolam lowers the oxygen
saturation levels, 30 min after administration, to a level significantly lower than that of the …

Prémédication par le midazolam intrarectal. Recherche de la dose efficace en anesthésie pédiatrique

C Saint-Maurice, C Estève, J Holzer, O Carrier… - Annales françaises d' …, 1984 - Elsevier
Premedication par le midazolam Recherche de la dose … 0,35 mg'kg ~ apparait comme la
dose suffisante de midazolam … the optimal dose of midazolam given per rectum which would …

Comparison of rectal to intramuscular administration of midazolam and atropine for premedication of children

PC De Jong, MP Verburg - Acta anaesthesiologica …, 1988 - Wiley Online Library
… Our goal was, therefore, to compare rectal to intramuscular administration of midazolam and
… that for anaesthetic premedication in children, rectal administration of midazolam and atro…