DNA methylation. The effect of minor bases on DNA-protein interactions
RLP Adams - Biochemical journal, 1990 - portlandpress.com
… in methyl transfer to DNA and the effect of methylation on DNA-protein interactions, with
particular … as minor bases, but rather as key bases which help regulate the functions of DNA. …
particular … as minor bases, but rather as key bases which help regulate the functions of DNA. …
The role of DNA shape in protein–DNA recognition
… of protein–DNA complexes, here we show that the binding of arginine residues to narrow
minor grooves is a widely used mode for protein–DNA … that narrow minor grooves strongly …
minor grooves is a widely used mode for protein–DNA … that narrow minor grooves strongly …
Protein and drug interactions in the minor groove of DNA
Z Morávek, S Neidle, B Schneider - Nucleic Acids Research, 2002 - academic.oup.com
… protein contacts with DNA are invariably through the major groove, apart from a few notable
exceptions such as the minor … minor groove contacts are common even for those proteins …
exceptions such as the minor … minor groove contacts are common even for those proteins …
DNA minor-groove recognition by small molecules
S Neidle - Natural product reports, 2001 - pubs.rsc.org
… One of the very few views of ternary drug–DNA–protein complexes at the atomic level is …
base-pair DNA sequence and a high-mobility-group (HMG) chromosomal architectural protein. …
base-pair DNA sequence and a high-mobility-group (HMG) chromosomal architectural protein. …
Minor groove-binding architectural proteins: structure, function, and DNA recognition
CA Bewley, AM Gronenborn… - Annual review of …, 1998 - annualreviews.org
… the HMG-box–containing proteins SRY and LEF-1.Each of these proteins interacts with DNA
exclusively through minor groovecontacts and alters DNA conformation. This paper reviews …
exclusively through minor groovecontacts and alters DNA conformation. This paper reviews …
Recognition of the four Watson–Crick base pairs in the DNA minor groove by synthetic ligands
S White, JW Szewczyk, JM Turner, EE Baird… - Nature, 1998 - nature.com
… However, no single protein structure motif has been identified that provides a general amino
acid–base pair code for the minor groove, although there has been remarkable progress …
acid–base pair code for the minor groove, although there has been remarkable progress …
The shape of the DNA minor groove directs binding by the DNA-bending protein Fis
S Stella, D Cascio, RC Johnson - Genes & development, 2010 - genesdev.cshlp.org
… average B DNA values, whereas the minor groove of high-… base pairs in the center is
unfavorable for Fis binding because of the increased conformational cost of compressing the minor …
unfavorable for Fis binding because of the increased conformational cost of compressing the minor …
Protein-DNA interactions: a structural analysis
… protein-protein interface sites. By looking at the number and positioning of protein residue-DNA
base interactions in a series of interaction footprints, three modes of DNA binding were …
base interactions in a series of interaction footprints, three modes of DNA binding were …
Structure‐based prediction of DNA target sites by regulatory proteins
… DNA target sequences for regulatory proteins. Pairwise potentials that determine the interaction
between bases … compatibility between DNA sequences and the protein–DNA complex …
between bases … compatibility between DNA sequences and the protein–DNA complex …
Protein–DNA hydrophobic recognition in the minor groove is facilitated by sugar switching
… DNA bases for proteins approaching the duplex in the minor groove. This is an important
result, since the protein–base … the pattern of donor and acceptor groups along the base edges. …
result, since the protein–base … the pattern of donor and acceptor groups along the base edges. …
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