The molecular basis of pluripotency in mouse embryonic stem cells

I Chambers - Cloning and stem cells, 2004 - liebertpub.com
Mouse embryonic stem (ES) cell self-renewal depends upon extrinsic signals from leukemia
inhibitory factor (LIF) and bone morphogenetic protein (BMP). These molecules activate, …

Two different evolutionary origins of stem cell systems and their molecular basis

K Agata, E Nakajima, N Funayama, N Shibata… - Seminars in cell & …, 2006 - Elsevier
… The vasa-like genes regulate reproductive stem cells, but not lineage-specific stem cells, which
… for the molecular basis for the evolutionary origin of these two different stem cell systems. …

Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network

G Huang, S Ye, X Zhou, D Liu, QL Ying - Cellular and molecular life …, 2015 - Springer
… Embryonic stem cells (ESCs) can be maintained in culture indefinitely while retaining the
capacity to generate any type of cell in the body, and therefore not only hold great promise for …

MicroRNome analysis unravels the molecular basis of SARS infection in bronchoalveolar stem cells

B Mallick, Z Ghosh, J Chakrabarti - PloS one, 2009 - journals.plos.org
… and functionally distinct epithelial stem cell populations which reside in distinct anatomical
locations. The basal cells [9], Clara cells [10] and type-II pneumocytes [11] are the candidate …

[PDF][PDF] Molecular basis of homing of intravenously transplanted stem cells to the marrow

M Tavassoli, CL Hardy - Blood, 1990 - researchgate.net
… To investigate the molecular basis of homing of intravenously transplanted stem cells to
the marr~w,~" mice are subjected to lethal doses of whole body irradiation. They are then …

Hierarchical and ontogenic positions serve to define the molecular basis of human hematopoietic stem cell behavior

F Shojaei, J Trowbridge, L Gallacher, L Yuefei… - Developmental cell, 2005 - cell.com
… The molecular basis governing functional behavior of human hematopoietic stem cells (HSCs)
is largely unknown. Here, using in vitro and in vivo assays, we isolate and define …

Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells

F Locatelli, D Pende, MC Mingari, A Bertaina… - Frontiers in …, 2013 - frontiersin.org
Frontiers | Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation
in the successful treatment of high-risk leukemias: role of alloreactive NK cells Skip to …

[HTML][HTML] The molecular basis for the cytokine-induced defect in homing and engraftment of hematopoietic stem cells

VM Berrios, GJ Dooner, G Nowakowski… - Experimental …, 2001 - Elsevier
… In an effort to determine the molecular basis for the engraftment defect induced by cell cycle
progression, we previously examined how the combination of IL-3, Il-6, IL-11, and SCF that …

Molecular basis of immortalization of human mesenchymal stem cells by combination of p53 knockdown and human telomerase reverse transcriptase overexpression

TM Liu, WM Ng, HS Tan, D Vinitha, Z Yang… - Stem cells and …, 2013 - liebertpub.com
… a new cellular model for basic studies of MSCs and understanding of the molecular basis of
… To decipher the molecular basis underlying transformation of p53 knockdown in MSCs, we …

Molecular mechanism to maintain stem cell renewal of ES cells

H Niwa - Cell structure and function, 2001 - jstage.jst.go.jp
… has to be kept stable during long-term culture in vitro, leading to the necessity of determining
the molecular basis for maintaining ES self-renewal. This paper summarizes the recent …