DNA methylation and cancer development: molecular mechanism

H Akhavan-Niaki, AA Samadani - Cell biochemistry and biophysics, 2013 - Springer
… the mechanism and cell regulatory effects of both hypo- and hyper-DNA methylation on
cancer… the effects of DNA methylation on cancer development. Indeed, alteration of the pattern of …

Cancer DNA methylation: molecular mechanisms and clinical implications

MT McCabe, JC Brandes, PM Vertino - Clinical Cancer Research, 2009 - AACR
… underlying the origins of cancer-specific DNA methylationmethylation is considered. Finally,
we discuss the clinical implications of aberrant DNA methylation and the utility of methylated

[HTML][HTML] Molecular mechanisms underlying the link between diet and DNA methylation

FZ Kadayifci, S Zheng, YX Pan - International journal of molecular …, 2018 - mdpi.com
methylation and demethylation. We also aim to go through all of the possible nutrient and
DNA methylation interactions in more detail, and examine the underlying mechanisms of these …

Molecular mechanisms of gene silencing mediated by DNA methylation

M Curradi, A Izzo, G Badaracco… - Molecular and cellular …, 2002 - Am Soc Microbiol
DNA methylation and … of DNA methylation can spread in cis and do not require promoter
modification. In order to investigate the molecular details of the inhibitory effect of methylation, …

[HTML][HTML] Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role

KS Crider, TP Yang, RJ Berry, LB Bailey - Advances in nutrition, 2012 - Elsevier
… on DNA methylation, there is enormous interest in assessing the potential for changes in folate
intake to modulate DNA methylation … This review highlights the role of DNA methylation in …

DNA methylation and epigenetic mechanisms

R Holliday - Cell biophysics, 1989 - Springer
methylation and the heritability of that pattern. There is strong evidence that DNA methylation
plays an … and on experimental studies at the molecular, chromosomal, and cellular levels. …

[图书][B] DNA Methylation: Basic Mechanisms

W Doerfler, P Böhm - 2006 - books.google.com
… in molecular medicine, a sound basic knowledge in the biology and biochemistry of DNA
methylation will … In this review, we focus on the molecules and mechanisms responsible for the …

[图书][B] Molecular biology of DNA methylation

RLP Adams, RH Burdon - 2012 - books.google.com
… have suggested several different roles for DNA methylation, and we expect that this flood
of information will continue. Of course DNA methylation may have multiple functions within a …

Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function

JS Hawe, R Wilson, KT Schmid, L Zhou… - Nature …, 2022 - nature.com
… between DNA sequence variation and DNA methylation … We identify 11,165,559 SNP–CpG
associations (methylation … We use molecular interaction and colocalization analyses to …

[HTML][HTML] DNA methylation dynamics in aging: how far are we from understanding the mechanisms?

F Ciccarone, S Tagliatesta, P Caiafa… - Mechanisms of ageing …, 2018 - Elsevier
molecular mechanisms that underpin aging-associated DNADNA methylation is currently
the most promising molecular … , the mechanisms underlying age-related DNA methylation