DNA methylation: a promising landscape for immune system-related diseases

B Suarez-Alvarez, RM Rodriguez, MF Fraga… - Trends in Genetics, 2012 - cell.com
DNA methylation, which is essential for the stability of gene expression during hematopoiesis.
Furthermore, aberrant DNA methylation … at the molecular level, this is not the case for DNA

[HTML][HTML] A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches

SH Parade, L Huffhines, TE Daniels, LR Stroud… - Translational …, 2021 - nature.com
… to enhance health outcomes among highly vulnerable children with this major adverse exposure.
… Studies have begun to explore DNA methylation as a measure of molecular aging, with …

Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo [a] pyrene exposure

J Corrales, X Fang, C Thornton, W Mei… - … and Physiology Part C …, 2014 - Elsevier
… Therefore, we hypothesized that BaP alters DNA methylation … , such as molecular modifications
of DNA (DNA methylation) … DNA hypomethylation may increase the vulnerability to many …

DNA methylation of cancer genome

HH Cheung, TL Lee, OM Rennert… - Birth Defects Research …, 2009 - Wiley Online Library
… Certain cancer types appear to be more vulnerable to epigenetic disruptions. According to
… the molecular mechanisms of DNA methylation in cancer during neoplastic transformation. …

[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
… is particularly vulnerable to epigenetic alterations. Dysregulations in the DNA methylation
process … spermatogenesis, suggesting a molecular link between DNA methylation and the PIWI/…

[HTML][HTML] Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets

EC Schwalbe, F Lafta, TM Barrow, G Strathdee - Oncogene, 2021 - nature.com
… -wide DNA methylation/expression data to identify cancer subtype-specific vulnerability
subtype-specific lethal genes, we found unique candidates in almost all molecular subtypes …

[HTML][HTML] Bridging basic and clinical research in early life adversity, DNA methylation, and major depressive disorder

A Brown, LM Fiori, G Turecki - Frontiers in Genetics, 2019 - frontiersin.org
DNA methylation has been implicated in ELA and MDD, and then examine how DNA
methylation … ELA related behavioral vulnerabilities that BDNF methylation alterations represent, …

[HTML][HTML] Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

BPF Rutten, E Vermetten, CH Vinkers, G Ursini… - Molecular …, 2018 - nature.com
… of genome-wide blood DNA methylation profiles in relation to … associated with alterations
in DNA methylation levels at 17 … in transgenerational inheritance of disease vulnerability. …

Preclinical and clinical evidence of DNA methylation changes in response to trauma and chronic stress

N Matosin, C Cruceanu, EB Binder - Chronic Stress, 2017 - journals.sagepub.com
… modifications, particularly DNA methylation, in response to … this may lead to vulnerability
to severe psychiatric disorders. … are molecules that induce and maintain global methylation

Successful treatment of post-traumatic stress disorder reverses DNA methylation marks

CH Vinkers, E Geuze, SJH van Rooij, M Kennis… - Molecular …, 2021 - nature.com
… -based genome-wide DNA methylation levels in relation to trauma… in DNA methylation at 12
differentially methylated regions (DMRs… was found for ZFP57 methylation changes related to …