Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.

T Kafri, M Ariel, M Brandeis, R Shemer… - Genes & …, 1992 - genesdev.cshlp.org
Methylation patterns of specific genes have been studied by polymerase chain reaction and …
in the germ line and early embryo. Some CpG sites are methylated in sperm DNA and …

Genome-wide methylation patterns in normal and uniparental early mouse embryos

SC Barton, KL Arney, W Shi, A Niveleau… - Human Molecular …, 2001 - academic.oup.com
… Two to 3% of embryos showed methylation patterns that were indistinguishable from those
in androgenetic embryos (Fig. 3B). One to 2% had one completely demethylated nucleus and …

DNA methylation pattern in human zygotes and developing embryos

H Fulka, M Mrazek, O Tepla, J Fulka - Reproduction, 2004 - rep.bioscientifica.com
… To test the specificity of this method, we first labeled 72 one-cell-stage mouse embryos
collected approximately 15–17 h after fertilization. In 66 of them, only the smaller pronucleus (…

Dynamic reprogramming of DNA methylation in the early mouse embryo

F Santos, B Hendrich, W Reik, W Dean - Developmental biology, 2002 - Elsevier
… approach the metaphase plate with their distinctive methylation patterns evident (maternal
on the left). This confirms the methylation patterns of the respective genomes prior to division. …

DNA methylation from embryo to adult

A Razin, T Kafri - Progress in nucleic acid research and molecular …, 1994 - Elsevier
methylation patterns in somatic tissues, methylation patterns undergo dynamic changes in the
embryo. … development of the implanted mouse embryo. In parallel, dynamic changes in the …

Changes in DNA methylation during mouse embryonic development in relation to X-chromosome activity and imprinting

M Monk - … Transactions of the Royal Society of London …, 1990 - royalsocietypublishing.org
patterns of methylation in mouse embryonic development: in the gametes, early embryos,
embryonic and extra-embryonic … by the inheritance of specific methylation patterns, how are we …

Targets and dynamics of promoter DNA methylation during early mouse development

J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
methylation in early mouse embryos, we optimized the MeDIP-on-ChiP procedure to
immunoprecipitate methylated … island methylation does not follow global DNA methylation

Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b

T Chen, Y Ueda, JE Dodge, Z Wang… - Molecular and cellular …, 2003 - Am Soc Microbiol
… novo methylation of the mouse genome during early embryonic … in maintaining global DNA
methylation patterns, we cultured … methylation status of various genomic sequences by using …

Programming of DNA methylation patterns

H Cedar, Y Bergman - Annual review of biochemistry, 2012 - annualreviews.org
… De novo establishment of a bimodal methylation pattern in the early embryo has far-reaching …
These results on a mouse model confirm the idea that DNA methylation patterns can be …

Methylation dynamics in the early mammalian embryo: implications of genome reprogramming defects for development

T Haaf - DNA methylation: development, genetic disease and …, 2006 - Springer
… 1 A–DA, B Parent-specific genome methylation patterns in early mouse embryos. Nuclei
were stained with fluorescein isothiocyanate (FITC)-conjugated anti-mC antibody (green) and …