Sex-dependent association between variability in infants' OXTR methylation at birth and negative affectivity at 3 months

S Nazzari, S Grumi, M Villa, F Mambretti… - …, 2022 - Elsevier
methylation of the oxytocin receptor gene (OXTR) have been shown in adults and are
related to several mental disorders. Negative affectivity … variations in OXTR methylation (OXTRm) …

The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review

C Maud, J Ryan, JE McIntosh, CA Olsson - BMC psychiatry, 2018 - Springer
… This review brings together early findings in a rapidly developing field of research,
examining relationships between DNA methylation (DNAm) of the Oxytocin Receptor Gene (OXTR) …

Methylation of the oxytocin receptor gene mediates the effect of adversity on negative schemas and depression

RL Simons, MK Lei, SRH Beach… - Development and …, 2017 - cambridge.org
… For example, like virtually every other methylation study, our assessment of OXTR methylation
was limited to a single point in time. Although adult adversity was related to methylation of …

[HTML][HTML] Oxytocin system gene methylation is associated with empathic responses towards children

H Spencer, FHP Lesemann, EJ Kraaijenvanger… - …, 2022 - Elsevier
… Next, we tested the effects of OXT and OXTR methylation on … Moreover, low OXTR methylation
levels were associated with … and negative pictures compared to high OXTR methylation

Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness

JP Gouin, QQ Zhou, L Booij, M Boivin, SM Côté… - Scientific Reports, 2017 - nature.com
… the associations between OXTR methylation and childhood … with greater OXTR methylation,
that OXTR methylation would … a stronger association between ELA and OXTR methylation. …

Oxytocin receptor gene methylation as a molecular marker for severity of depressive symptoms in affective disorder patients

B Ludwig, L Carlberg, K Kienesberger, P Swoboda… - BMC psychiatry, 2022 - Springer
… to an increased methylation status of the Oxytocin receptor (OXTR) … that methylation levels
(%) of the oxytocin receptor promoter … within this present sample of affective disorder patients. …

[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies

EJ Kraaijenvanger, Y He, H Spencer, AK Smith… - Neuroscience & …, 2019 - Elsevier
… Here, we systematically reviewed all human studies (n = 30) discussing OXTR methylation
in relation to socio-behavioral phenotypes. As such, we provide a complete and up-to-date …

OXTR methylation modulates exogenous oxytocin effects on human brain activity during social interaction

X Chen, S Nishitani, E Haroon… - Genes, Brain and …, 2020 - Wiley Online Library
… whether DNA methylation of OXTR modulates the effect of intranasal OT on the neural
response to positive and negative social interactions in the PD game. OXTR methylation did not …

DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology

K Lancaster, L Goldbeck, MH Puglia… - … and affective …, 2018 - academic.oup.com
… Our results demonstrate that OXTR methylation is negatively associated with resting
parasympathetic tone and that this relationship is mediated by structural differences in the central …

Interactions between oxytocin receptor gene methylation and callous-unemotional traits impact socioaffective brain systems in conduct-disordered offenders

M Aghajani, ET Klapwijk, OF Colins, C Ziegler… - Biological Psychiatry …, 2018 - Elsevier
OXTR methylation (OXTR Meth ) on actual OXTR expression is rather complex, though, and
recent data suggest that different OXTR … For instance, while DNA methylation at the promoter …