… the treatment of neonatal seizures with newer antiepileptic drugs. We hypothesized that 2
drugs, … more frequently than other newer antiepileptic drugs, and we focused on these agents. …

… Phenobarbital remains the first-line drug for treatment of neonatal seizures, despite having
only … for neonatal seizures and there is considerable off-label use of antiepileptic medications …

… The lack of efficacy of conventional antiepileptic drugs has lead clinicians to explore other
means of treating neonatal seizures. One strategy has been to use our understanding of the …

… as the first-line drug for neonatal seizures. In addition, there is a tendency for levetiracetam
to be an effective second-line treatment for neonatal seizures after failure of first-line drugs. …

… treat neonatal seizures (ie primarily first generation antiepileptics… second-generation
antiepileptic drugs in neonates. The aim of … of neonatal seizures in both term and preterm infants. …

… an increased risk of epilepsy later in life. Phenobarbital and phenytoin remain the antiepileptic
drugs (AEDs) most commonly used to treat neonatal seizures, despite their suboptimal …

… In clinical practice, EEGs are often ordered after administration of antiepileptic drugs (AEDs).
In contrast, with clinical practice in older age groups, a full loading dose of an AED (most …

… pharmacological therapy for neonatal seizures. Our objective was to determine which
antiepileptic medication or medications are most effective for treating neonatal seizures, to guide …

… of performing a lumbar puncture after a neonatal seizure. The most commonly isolated
pathogens … against any potential deleterious effects of anticonvulsant medication. It is this second …

… Neonatal seizures constitute the most frequent presenting … in neonatal HIE, the most frequent
cause of neonatal seizures, … Data indicate that hypothermia itself is likely to reduce seizure …