DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis

G Mayol, JI Martín-Subero, J Ríos, A Queiros, M Kulis… - PloS one, 2012 - journals.plos.org
DNA methylation-specific microarrays. Besides identifying changes globally associated with
NB, we characterized DNA methylation … -specific loss of DNA methylation is more prevalent …

Epigenetic dysregulation in neuroblastoma: A tale of miRNAs and DNA methylation

F Parodi, R Carosio, M Ragusa, C Di Pietro… - … et Biophysica Acta (BBA …, 2016 - Elsevier
DNA methylation can interfere with gene expression acting at distance through the
methylation or … We have analyzed the methylation status of a set of miRNAs in a panel of …

Epigenetic approaches in neuroblastoma disease pathogenesis

FF Caputi, S Candeletti… - Neuroblastoma-Current …, 2017 - books.google.com
pathophysiology of neuroblastoma, are still poorly known. In this frame, preclinical studies
have demonstrated that the DNA methylationNeuroblastoma growth might be closely related …

The role of genetic and epigenetic alterations in neuroblastoma disease pathogenesis

R Domingo-Fernandez, K Watters, O Piskareva… - Pediatric surgery …, 2013 - Springer
… caused by multiple mechanisms, including aberrations in DNA copy number, altered
transcriptional activators/repressors, aberrant DNA methylation, or defects of the proteins involved …

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

S Gómez, G Castellano, G Mayol, M Suñol… - …, 2015 - Taylor & Francis
… fingerprint of neuroblastoma provides new insights into the pathogenesis and clinical … of
the DNA methylation landscape of neuroblastoma, we investigated 35 primary neuroblastoma

[HTML][HTML] Methylation of DNA and chromatin as a mechanism of oncogenesis and therapeutic target in neuroblastoma

RMR Kumar, NF Schor - Oncotarget, 2018 - ncbi.nlm.nih.gov
… contributes significantly to the pathogenesis of NB and may … DNA methylation attenuates
gene expression by the addition … mechanisms that result from DNA methylation remain to be …

Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs

S Das, K Bryan, PG Buckley, O Piskareva, IM Bray… - Oncogene, 2013 - nature.com
DNA hypermethylation of miRNA regulatory regions contributes toward their transcriptional
silencing in neuroblastoma. The … to be regulated by DNA methylation in other forms of cancer. …

DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis

G Mayol Ricart, JI Martín-Subero, J Ríos… - … , vol. 7, num. 11, p. 1-8, 2012 - diposit.ub.edu
DNA methylation profiling and identification of differentially methylated genes in NB In
order to investigate the pattern of DNA methylation in NB, we analyzed 22 primary NB tumors …

MicroRNA and DNA methylation alterations mediating retinoic acid induced neuroblastoma cell differentiation

RL Stallings, NH Foley, IM Bray, S Das… - Seminars in cancer …, 2011 - Elsevier
… and DNA methylation alterations in the process of neuroblastoma cell … and DNA methylation
changes in regulating neuroblastoma cell … MicroRNAs and neuroblastoma pathogenesis

Genome‐wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma

J Charlet, A Tomari, AR Dallosso… - Molecular …, 2017 - Wiley Online Library
neuroblastoma pathogenesis, silencing neuroblastoma suppressor genes by aberrant promoter
DNA hypermethylation… -22, or by aberrant histone methylation, for example, CASZ1, CLU…