… In both cases, we confirmed a correlation between nucleosome depletion and CGI length; …
largest CpG content (Supplemental Fig. 3A). Finally, the position of the major nucleosome in …

… Although most genomic DNA is occupied by nucleosomes, … , are depleted of nucleosomes
or have lower nucleosome … CpG islands define the genome-wide pattern of nucleosome …

… that CpG islands were associated not only with methylation-free promoters but also with
nucleosome-… To assess whether the nucleosome depletion of CGIs is derived from sequence …

… nucleosome is associated with gene repression. The relationship between DNA methylation
and nucleosome … ) gene: a methylated CpG island prevents nucleosome depletion from the …

… a single-molecule, high-resolution nucleosome positioning assay, we demonstrate that
active, but not inactive, non-CpG island promoters display a nucleosome-depleted region (NDR) …

… CpG island as an example, we show that the switch between the two heritable states involves
the complete absence or presence of nucleosomes … To confirm the nucleosome depletion …

… that nucleosomes have a high intrinsic affinity for G+C and CpG … nucleosome-depleted CpG
promoters and nucleosome … of nucleosome occupancy within CpG and non-CpG promoter …

… CGIs for promoter function by destabilizing nucleosomes and attracting proteins that create
… G+C base composition, little CpG depletion, and frequent absence of DNA methylation. …

… low nucleosome occupancy at promoters in this class can be attributed to the assembly of
CpG islands into unstable nucleosomes… Because CpG dinucleotides have been depleted from …

… with CpG island hypermethylation and loss of nucleosomes at promoters, but the role of
nucleosome … and nucleosome occupancy (NOMe-seq). We find that the genomic location of …