… tumors from 33 cancer types, we present our current understanding of the molecular
processes governing oncogenesis. We illustrate our insights into cancer through synthesis of the …

… oncogenic pathways by integrating TCGA pan-cancer data sets. Multi-omics analysis showed
oncogenic … multiple omics data of pan-cancers from The Cancer Genome Atlas (TCGA) [4], …

… of oncogenic processes and by the resulting variation in therapeutic responses. Projects
such as The Cancer Genome Atlas (… We refer to this trend as the cancer genome hyperbola. …

… Gene selection for MP has focused on oncogenes, tumor suppressor genes, and
genomic stability genes. However, we believe that to fully implement PCM, germline genetic …

… , can occur “completely independently of oncogenic or tumor suppressor or mismatch repair
mutations and would not be detected by a human cancer genome sequencing effort. [….] A …

… a number of cancer genome profiles by whole-genome sequencing (WGS). To explore cancer
genomic alterations and their diversity comprehensively, global and local cancer genome-…

… and oncogenesis. … the field of genomics, many laboratories around the world are working
together as part of the International Cancer Genome Consortium, or collaborating in the Cancer …

… cancer genome projects produced multi-dimensional genome-wide big data such as The
Cancer Genome … Sanger Institute's Cancer Genome Project [8], and the International Cancer …

… A majority of cancers are driven by genomic alterations that dysregulate key oncogenic
pathways … hypothesis of the cancer genome era: The use of cancer genomic information to guide …

… The focus of this review is on cancer genes that could be identified by genomic … to oncogenes,
since it is much easier to pharmacologically reduce the activity of a hyperactive oncogene …