… Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental … imprints — that are laid down in the parental …

… Genomic imprinting describes a form of non-Mendelian gene expression, in which the expression
of an allele depends on its parent of … advantage of genomic imprinting: EVOLVABILITY …

… parental alleles (that is, allow the identification of parent-of-origin effects), so the number and
effects of imprinted genes … that consider genetic and epigenetic variation at imprinted loci as …

… Moreover, imprinting has recently … Genetic studies indicate that imprinting of particular
chromosomal regions in the mouse may result in differential gene expression of parental alleles“. …

… parent-of-origin–restricted expression, phenotypes determined by imprinted genes are
susceptible not only to genetic … in setting the genomic imprint and in altering the patterns of gene …

… Diploid cells thus contain two parental copies (or parental alleles) of each autosomal
gene, which are predicted to show the same transcription state since for the majority of …

… genetic alleles as descendent from father or mother, genomic imprints have the significant
functional … of stifling gene expression from one of the parental alleles, resulting in unbalanced …

… depending on its parental origin. We show that genomic imprinting evolves easily if females
… in transgenes reflects the genomic imprinting of endogenous genes, and confirmed that the …

… Parental origin of the expressed allele Finally, to assign parental origin to the expressed
allele, we examined genomic DNA from peripheral blood of available parents of the …

… that only a single parental allele is expressed. These genes, which are termed “imprinted,”
are dependent on the epigenetic machinery for their initial designation of parental identity …