Passive and active DNA methylation and the interplay with genetic variation in gene regulation

M Gutierrez-Arcelus, T Lappalainen, SB Montgomery… - elife, 2013 - elifesciences.org
DNA methylation variation in different dimensions. Our results reveal a picture where DNA
methylationpassive or active nature. We further highlight some of the mechanisms by which …

A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants

A Sadakierska-Chudy, RM Kostrzewa, M Filip - Neurotoxicity research, 2015 - Springer
… regulation, as well as DNA damage repair. In this review… DNA methylation, cytosine derivatives,
active and passive demethylation pathways as well as histone variants. DNA methylation

Getting rid of DNA methylation

FM Piccolo, AG Fisher - Trends in cell biology, 2014 - cell.com
… In mammals, passive loss of DNA methylation has been observed on fertilization and in
gametogenesis (Figure 2B). Following fertilization, the maternally derived genome is …

[HTML][HTML] DNA methylation signature of passive smoke exposure is less pronounced than active smoking: The Understanding Society study

PM Hulls, F de Vocht, Y Bao, CL Relton… - Environmental …, 2020 - Elsevier
… The extent of the biological impact of passive smoke exposure is unclear. We sought to
investigate the association between passive smoke exposure and DNA methylation, which could …

DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
DNA methylation and demethylation in the nervous system. We will describe the DNA (de)methylation
Passive DNA demethylation occurs in dividing cells. As Dnmt1 actively maintains …

Active turnover of DNA methylation during cell fate decisions

A Parry, S Rulands, W Reik - Nature Reviews Genetics, 2021 - nature.com
… greater rates of passive demethylation (through infidelity of DNMT1 and UHRF1) than active
… a much greater influence on methylation levels than passive demethylation at the majority of …

Active DNA demethylation and DNA repair

C Niehrs - Differentiation, 2009 - Elsevier
DNA methylation is a dynamic process as will be discussed in this review. While the main
focus of the DNA methylation … exclusion of DNA methyltransferases, passive demethylation of …

New concepts in DNA methylation

A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
… , but can be lost through passive or active demethylation and the new methylation can be
introduced as well. Typically, Dnmt1 is considered to be a maintenance enzyme, whereas …

Genomic patterns and context specific interpretation of DNA methylation

T Baubec, D Schübeler - Current opinion in genetics & development, 2014 - Elsevier
… The important aspect of active and passive DNA de-methylation has recently been
reviewed … DNA repair enzymes have been proposed to be involved in active DNA de-methylation

Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

J Arand, M Wossidlo, K Lepikhov, JR Peat, W Reik… - Epigenetics & …, 2015 - Springer
… We conclude that a combination of passive and active … Next, we investigated the effect of
blocking all DNA methylation … in DNA methylation patterns that are attributable to active DNA