… DNA Methylation Genome-wide DNA methylation arrays currently examine 850,000 CpG …
These analyses suggest that DNA methylation plays a major role in the pathogenesis of MB …

… We found that DNA methylation profiling discloses significant advantages for molecular
diagnostic of WNT MB. All other “routine” methods applied, such as ß-catenin …

… In particular, DNA methylation profiling has emerged as a … malignant pediatric brain
tumors, namely medulloblastoma, … the potential role of DNA methylation profiling as a frontline …

… This DNA hypermethylation has been correlated with … a genomewide DNA methylation assay
that identifies CpG methylation on … (T m ) of DNA. We show that this denaturation analysis of …

… Medulloblastoma (MB), the most common form of pediatric brain malignancy, has a low
frequency of oncogenic mutations but pronouncedly abnormal DNA methylation changes. …

… Among the four medulloblastomas, three could be further subgrouped … medulloblastoma
tumor groups, but one case did not share the methylation profile of any of the medulloblastoma …

… We demonstrate, however, that cancer-specific gain of DNA methylation in DMVs is also
linked to reactivation of repressed genes. This relationship is similar to that observed previously …

… DNA methylation was measured in archival peripheral blood samples collected on 56
pediatric medulloblastoma patients. Hazard ratios (HR) and 95% confidence intervals (CI) for the …

… It is now clear that medulloblastoma (MB), one of the most clinically challenging paediatric
brain tumours, is not a single disease entity. Rather, it comprises four distinct molecular …

… DNA methylation profiles on pediatric medulloblastoma … Medulloblastoma is the most frequent
malignant pediatric brain … ERCC2 DNA methylation profiles on pediatric medulloblastoma …