… However, each subgroup was not overlooked in the interpretation of our results because
they exhibit different prognostic characteristics, as Group 3 is prognostically unfavorable than …

… temperature of methylated DNA, termed denaturation analysis of methylation differences (…
of cancer-specific methylation changes in primary medulloblastomas in critical developmental …

… methylation occurs across subgroups in medulloblastoma [14… due to either the difference
between the complete deletion of … of other models of pediatric brain tumors. Several companies …

… the DNA methylation data are robust and reliable to discriminate between different molecular
… correlating with clinical or molecular differences, including mutational landscape (with and …

… malignant pediatric brain tumors, namely medulloblastoma, … the potential role of DNA
methylation profiling as a frontline … highlighted key differences between pediatric CNS tumors …

… medulloblastoma tumor groups, but one case did not share the methylation profile of any of
the medulloblastoma … in tumors of different histological types from different anatomical sites. …

… of aPRIMES in detecting the methylation status of CpG islands for different states of … To test
the performance of aPRIMES, we analyzed CGI methylation in 20 pediatric medulloblastomas …

… In parallel, to estimate the individual variations of these DNA epigenetic markers, we
performed pairwise comparisons of the CSF ctDNA methylation and hydroxymethylation data …

… children and limiting it to children would have greatly diminished our sample size. It may
be that pediatric and young adult medulloblastomas have different sex-specific methylation …

… Next, we focused on methylation differences spatially within the tumours and calculated the
… Methylation classification of medulloblastoma was thus stable across time and space in our …