Oral transmucosal drug delivery for pediatric use

JKW Lam, Y Xu, A Worsley, ICK Wong - Advanced drug delivery reviews, 2014 - Elsevier
transmucosal delivery has emerged as an attractive route of administration for pediatric
patients… common oral transmucosal routes of administration, are focused in this review. The oral …

Transmucosal administration of midazolam for premedication of pediatric patients: comparison of the nasal and sublingual routes

HW Karl, JL Rosenberger, MG Larach… - The Journal of the …, 1993 - pubs.asahq.org
… Background: Nasal transmucosal midazolam is effective for premedication of pediatric
patients; however, 61–74% of these patients cry at nasal drug administration. Sublingual benzo…

Novel delivery systems: oral transmucosal and intranasal transmucosal

TH Stanley, MA Ashburn - Journal of pain and symptom management, 1992 - Elsevier
… Oral transmucosal fentaayl citrate has been evaluated as a pranedication in the pediatric
instance, when compared with orally administered drugs, transdermal and transmucosal

Comparison between three transmucosal routes of administration of midazolam in children

G Geldner, M Hubmann, R Knoll… - Pediatric …, 1997 - Wiley Online Library
administration with the fewest adverse effects and the best … min; Measure= transmucosal
midazolam application to obtain … of three transmucosal routes of midazolam administration in …

The use of oral transmucosal fentanyl citrate for painful procedures in children

NL Schechter, SJ Weisman, M Rosenblum… - …, 1995 - publications.aap.org
… To investigate the efficacy and safety of oral transmucosal fentanyl (OTFC) in providing …
Forty-eight children referred to the University of Connecticut Division of Pediatric Hematology/ …

Premedication of pediatric tonsillectomy patients with oral transmucosal fentanyl citrate

RM Dsida, M Wheeler, PK Birmingham… - Anesthesia & …, 1998 - journals.lww.com
… , oral, oral transmucosal, IM, IV, and rectal. Each medication and route of administration has
… ) was developed to ease premedication administration and improve patient acceptance. This …

Pharmacokinetics of lidocaine delivered from a transmucosal patch in children.

A Leopold, S Wilson, JS Weaver, AM Moursi - Anesthesia progress, 2002 - ncbi.nlm.nih.gov
… than in adults and were high enough to require inclusion in the calculation of total lidocaine
administered to a pediatric patient. Key Words: Lidocaine; Transmucosal patch; Children. …

Buccal dosage forms: general considerations for pediatric patients

S Montero-Padilla, S Velaga, JO Morales - AAPS PharmSciTech, 2017 - Springer
… and requirements relevant to buccal administration for pediatric patients (compared to
adults… absorption, may result in swallowing before transmucosal absorption can take place (4). …

Feasibility of a comfort care protocol using oral transmucosal medication delivery in a palliative neonatal population

C Drolet, H Roy, J Laflamme… - Journal of Palliative …, 2016 - liebertpub.com
… Background: The oral transmucosal (OTM) route for administration of comfort medication
in infants at the end-of-life has long been favored by our pediatric palliative care team but has …

Oral transmucosal midazolam premedication for preschool children

UA Pandit, PJ Collier, S Malviya… - Canadian journal of …, 2001 - Springer
… Conclusion: Oral midazolam in thick strawberry syrup, administered in small aliquots via
the oral transmucosal route was well accepted and proved to be an effective premedicant in …