… of midazolam be avoided in all cases, and continuous infusion is to be preferred, possibly
using a higher initial dose in order to obtain rapid sedation. In addition, midazolam should be …

… In obese patients receiving continuous infusions of midazolam, the infusion rate should
be adjusted to ideal rather than total body weight because midazolam clearance does not …

… and midazolam in intensive care patients. The objective of this study was to compare the …
pharmacokinetics of lorazepam and midazolam after long-term continuous infusion in …

… The pharmacokinetics of midazolam and its metabolites were studied in 17 patients on …
unit who were receiving a continuous intravenous infusion of midazolam, adjusted according to …

… The relatively rapid elimination makes midazolam suitable for use by infusion in a total iv …
with the opioid drug alfentanil, midazolam showed a pharmacokinetic behaviour not unlike that …

… One patient received a continuous infusion of midazolam for the treatment of status … efficacy
and pharmacokinetics of midazolam, and its metabolites, during and after long-term infusion. …

… with both intermittent and continuously infused sedatives.Unfortunately, the pharmacokinetics
of midazolam change significantly during long periods of continuous infusions.…

… The present study was performed to elucidate the pharmacokinetic behaviour of midazolam
following intravenous and oral dose administration and to calculate its bioavailability. …

… rate of iv infusion of midazolam in ICU patients was adjusted individually to between 6 and
15 mg/hr. Blood samples were taken during and after the continuous infusion of midazolam. …

… midazolam in young and elderly male volunteers. To quantify the concentration-effect relationship
of midazolam, pharmacokinetic… of midazolam delivered during each infusion cycle and …