[HTML][HTML] Population-specificity of human DNA methylation

HB Fraser, LL Lam, SM Neumann, MS Kobor - Genome biology, 2012 - Springer
… one African and one European population. We find population-specific patterns of DNA
methylation at over a third of all genes. Furthermore, although the methylation at over a thousand …

DNA methylation-based variation between human populations

F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
… in DNA methylation patterns between various populations (pop… variation in DNA methylation
among human population and … The primer sets targeted 15 CpG sites and Sp1 (specificity

DNA Methylation as a Cancer‐Specific Biomarker: From Molecules to Populations

A Patel, JD Groopman, A Umar - … of the New York Academy of …, 2003 - Wiley Online Library
… and specificity.’20 The reproducibility, sensitivity and specificity of the method selected to
assess DNA methylation … Both the sensitivity and specificity of diagnostic tests depends on the …

Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
… includes assessment of the impacts of sex, functional consequence, and tissue specificity
on DNA methylation response. Taken together these studies suggest that arsenic-associated …

DNA methylation profiling reveals the presence of population-specific signatures correlating with phenotypic characteristics

AK Giri, S Bharadwaj, P Banerjee… - Molecular genetics and …, 2017 - Springer
… intra-population variations in DNA methylation levels within … population as compare to
Caucasian or African population who … show population specificity using genome wide methylation

Accounting for population stratification in DNA methylation studies

RT Barfield, LM Almli, V Kilaru, AK Smith… - Genetic …, 2014 - Wiley Online Library
… SNP)‐based PCs, followed by methylation‐based PCs, which … Among our different approaches
to computing methylation‐… adjust for population stratification in DNA methylation studies …

DNA methylation contributes to natural human variation

H Heyn, S Moran, I Hernando-Herraez… - Genome …, 2013 - genome.cshlp.org
… Furthermore, we aimed to interrogate the tissue specificity of epitype–genotype associations
… , we aimed to determine DNA methylation differences between human populations and their …

[HTML][HTML] Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

LT Husquin, M Rotival, M Fagny, H Quach, N Zidane… - Genome biology, 2018 - Springer
… We therefore investigated the population specificity of the 69,702 meQTL-CpGs detected
using a model selection approach (see “Materials and methods”). We found 2868 (4.1%) …

Differential DNA methylation analysis optimally requires purified cell populations

MK Skinner - Fertility and sterility, 2016 - fertstert.org
… help provide cell specificity, the use of a mixed cell population in the analysis of DNA
methylation is a reflection of all cell types present. Therefore, changes in cell population number or …

[HTML][HTML] Accurate ethnicity prediction from placental DNA methylation data

V Yuan, EM Price, G Del Gobbo, S Mostafavi… - Epigenetics & …, 2019 - Springer
… This finding, together with EPISTRUCTURE—a method that also relies on mQTLs [9]—suggests
that leveraging the tissue- and population-specificity of mQTLs can produce highly …