Estimating cell-type-specific DNA methylation effects in heterogeneous cellular populations

YCA Feng, Y Guo, L Pain, GM Lathrop, C Laprise… - …, 2021 - Taylor & Francis
… Epigenetic modifications, particularly DNA methylation at … its each accessibility to measure
DNA methylation levels of an … and cell-type specificity of DNA methylation patterns ( Figure 1 …

Variation in DNA methylation is not consistently reflected by sociality in Hymenoptera

KM Glastad, SV Arsenault, KL Vertacnik… - Genome biology and …, 2017 - academic.oup.com
… The ortholog groups in our data that exhibit high taxonomic specificity in DNA methylation
… Variation in effective population size is also expected to influence the efficiency of purifying …

Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis

H Kelly, Y Benavente, MA Pavon, S De Sanjose… - British journal of …, 2019 - nature.com
… and relative specificity of DNA methylation markers compared … genes DNA methylation assays
among populations with high … higher specificity compared to primary HPV DNA screening, …

Development of super-specific epigenome editing by targeted allele-specific DNA methylation

N Rajaram, AG Kouroukli, S Bens, P Bashtrykov… - Epigenetics & …, 2023 - Springer
… maximum DNA methylation with highest allelic specificity in … to five to tenfold stronger average
DNA methylation at the on-… ), which occur on a population level with a frequency of one per …

DNA methylation profiles and their diagnostic utility in BC

M Shan, L Zhang, Y Liu, C Gao, W Kang… - Disease …, 2019 - Wiley Online Library
methylated biomarkers that included these three genes showed the best sensitivity and
specificity … add more effective methylation markers to increase the sensitivity and specificity of this …

Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

LE Reinius, N Acevedo, M Joerink, G Pershagen… - PloS one, 2012 - journals.plos.org
DNA methylation analyses, all the following analyses were restricted to compare each cell
population … The current lack of information regarding cell specificity imposes a limitation for the …

Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase

R Goyal, R Reinhardt, A Jeltsch - Nucleic acids research, 2006 - academic.oup.com
… the specificity of the Dnmt1 enzyme for hemimethylated DNA … of the propagation of a DNA
methylation pattern, we apply … DNA methylation (31,33) and started with two populations of …

Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

M Machin, AFS Amaral, M Wielscher, FI Rezwan… - BMC pulmonary …, 2017 - Springer
… This systematic review assesses the association of lung function and chronic obstructive
pulmonary disease (COPD) with DNA methylation profiles in peripheral blood from population-…

[HTML][HTML] Diagnostic DNA methylation biomarkers for renal cell carcinoma: a systematic review

K Lommen, N Vaes, MJ Aarts, JG van Roermund… - European Urology …, 2021 - Elsevier
specificities. Overall, large methodological differences were observed between studies,
including differences in DNA methylation detection techniques, study population… and specificities

DNA methylation arrays as surrogate measures of cell mixture distribution

EA Houseman, WP Accomando, DC Koestler… - BMC …, 2012 - Springer
… lineages with high sensitivity and specificity[4] and considerable … population data, it is
possible to use S 0 to predict distribution of leukocytes in a single sample having DNA methylation