Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison

T De Meyer, P Bady, G Trooskens, S Kurscheid… - Scientific reports, 2015 - nature.com
… Moreover, in the population under study, overall conclusions were in line with MSP results
… on our conclusions regarding sensitivity and specificity. Indeed other potential sources of …

Dynamic DNA methylation: In the right place at the right time

C Luo, P Hajkova, JR Ecker - Science, 2018 - science.org
… through the modulation of their binding affinity and specificity … Developing tissues contain
heterogeneous cell populations … contributed by distinct cell populations. Improvements in single-…

Identification and evaluation of age-correlated DNA methylation markers for forensic use

JL Park, JH Kim, E Seo, DH Bae, SY Kim… - Forensic Science …, 2016 - Elsevier
DNA methylation markers may be useful for age prediction in samples from Asian populations
We expect that our extensive DNA methylation study and DNA methylation markers will be …

Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

PJ Hop, R Luijk, L Daxinger, M Van Iterson, KF Dekkers… - Genome biology, 2020 - Springer
… that affect DNA methylation patterns in blood using large-scale population genomics data. …
expression and distant DNA methylation levels, while ensuring specificity of the associations …

Diagnostic utility of genome-wide DNA methylation testing in genetically unsolved individuals with suspected hereditary conditions

E Aref-Eshghi, EG Bend, S Colaiacovo… - The American Journal of …, 2019 - cell.com
… of genome-wide DNA methylation analysis of peripheral blood … of 14 syndromes using DNA
methylation data with full accuracy. … This study demonstrates that genomic DNA methylation

DNA methylation as a biomarker of aging in epidemiologic studies

U Lim, MA Song - Cancer Epigenetics for Precision Medicine: Methods …, 2018 - Springer
… These DNA methylation age estimates have … populations. Moreover, an increasing number
of epidemiologic studies have demonstrated an independent association of DNA methylation

DNA methylation age of human tissues and cell types

S Horvath - Genome biology, 2013 - Springer
… I propose that DNA methylation age measures the cumulative effect of an epigenetic
maintenance system. This novel epigenetic clock can be used to address a host of questions in …

Latest techniques to study DNA methylation

Q Gouil, A Keniry - Essays in biochemistry, 2019 - portlandpress.com
… difficult to surmount, among which DNA degradation, lack of specificity, or short reads with
… only provide average measurements across bulk cell populations. Now single-cell genomics …

DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project

VK Rakyan, T Hildmann, KL Novik, J Lewin, J Tost… - PLoS …, 2004 - journals.plos.org
… This occurs because a population of bisulphite PCR products generated from a … However,
the extent of tissue specificity of DNA methylation profiles is relatively unknown. The HEP pilot …

Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function

JS Hawe, R Wilson, KT Schmid, L Zhou… - Nature …, 2022 - nature.com
… Cell type specificity of iQTL is supported by the high replication rates of iQTL in isolated … in
mixed cellular populations, we extended our analyses to identify cell lineage- and population-…