… The most commonly used antifibrinolytic drug, tranexamic acid, is associated with an
increased incidence of postoperative seizures. The reported increase in the frequency of …

… in the incidence of postoperative convulsive seizures from 1.3% … the initial use of high-dose
tranexamic acid (TXA) therapy after … between TXA usage and seizures after cardiac surgery. …

… Abstract Background Seizures after cardiac surgery are a serious … agent tranexamic acid
(TA), which has known proconvulsant properties, may be associated with postoperative seizures…

… the association of seizures with tranexamic acid 9-11. … the burden imposed by postoperative
convulsive seizures in cardiac … tranexamic acid is an independent predictor of postoperative …

… suggest that tranexamic acid (TA) can induce seizure activity in the postoperative period. To
… An association between high preoperative creatinine value and postoperative seizure was …

… of postoperative seizures [4], [5]. However, the prevalence and the odds ratio comparing with
non-TXA exposure with dose–effect response of tranexamic acid-associated seizures have …

… of seizures after CPB and the clinical outcomes of patients with postoperative seizure in a …
The contribution of tranexamic acid to postoperative seizure and a potential dose-response …

… postoperative bleeding remained available: tranexamic acid (TXA) and ε-aminocaproic acid
(… a strong correlation between TXA treatment and seizures after cardiac surgery (defined as …

… Besides the antifibrinolytic agent, three other variables differed significantly between
patients with and without postoperative seizures: age (mean (SD), 77.0 (5.9) years vs 73.2 (9.0) …

… In conclusion, we have demonstrated an increased incidence of postoperative seizures
in patients who have undergone open-chamber cardiac surgery and received TxA. This …