Targets and dynamics of promoter DNA methylation during early mouse development
J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
… use it to profile DNA methylation during early development of the mouse embryonic … DNA
methylation is targeted to specific gene promoters during implantation and that this methylation …
methylation is targeted to specific gene promoters during implantation and that this methylation …
DNA methylation in early development
TM Geiman, K Muegge - … Reproduction and Development …, 2010 - Wiley Online Library
… DNA methylation are an important part of this process. This review looks at the role of DNA
methylation in early embryonic development… CpG promoters have low DNA methylation levels …
methylation in early embryonic development… CpG promoters have low DNA methylation levels …
DNA methylation profile of the mouse skeletal α-actin promoter during development and differentiation
PM Warnecke, SJ Clark - Molecular and cellular biology, 1999 - Taylor & Francis
… being extensively methylated and others sparsely methylated. Moreover… mouse does not
correlate with the methylation state of the promoter, as we find a similar low level of methylation …
correlate with the methylation state of the promoter, as we find a similar low level of methylation …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… different developmental stages. In this Review, we discuss the mechanisms and functions
of DNA methylation and demethylation in both mice and humans at CpG-rich promoters, gene …
of DNA methylation and demethylation in both mice and humans at CpG-rich promoters, gene …
DNA methylation homeostasis in human and mouse development
… role of DNA methylation when present at promoter or … DNA methylation and its oxidised
forms 5hmC and 5-formylcytosine (5fC) in gametes and early mouse embryos and by methylation …
forms 5hmC and 5-formylcytosine (5fC) in gametes and early mouse embryos and by methylation …
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
CR Farthing, G Ficz, RK Ng, CF Chan, S Andrews… - PLoS …, 2008 - journals.plos.org
… DNA methylation patterns are reprogrammed in primordial … and subsequent de novo
methylation. It has been suggested … genome-wide promoter analysis of DNA methylation in mouse …
methylation. It has been suggested … genome-wide promoter analysis of DNA methylation in mouse …
DNA methylation in mammalian development and disease
W Dean, D Lucifero, F Santos - … Research Part C: Embryo …, 2005 - Wiley Online Library
… from their viral promoters would result in … in early development and germ cell differentiation
in humans will influence our understanding of the potential impact of DNA methylation in …
in humans will influence our understanding of the potential impact of DNA methylation in …
DNA methylation reprogramming of functional elements during mammalian embryonic development
… We plotted the DNA methylation levels of promoters and genic regions for each … early mouse
embryogenesis 13 . Our data also showed that genes exhibiting hypomethylated promoters …
embryogenesis 13 . Our data also showed that genes exhibiting hypomethylated promoters …
DNA methylation: roles in mammalian development
ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
… Before exploring dynamic regulation within selected cellular systems, we provide a
breakdown of DNA methylation as it acts on promoters, repetitive elements and parent-specific …
breakdown of DNA methylation as it acts on promoters, repetitive elements and parent-specific …
Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity
T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… We establish that DNA methylation of CpG-island promoters is a primary and causal silencing
mechanism for restricting ectopic expression of a large panel of germline genes. While we …
mechanism for restricting ectopic expression of a large panel of germline genes. While we …
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