Targets and dynamics of promoter DNA methylation during early mouse development

J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
… use it to profile DNA methylation during early development of the mouse embryonic … DNA
methylation is targeted to specific gene promoters during implantation and that this methylation

DNA methylation in early development

TM Geiman, K Muegge - … Reproduction and Development …, 2010 - Wiley Online Library
DNA methylation are an important part of this process. This review looks at the role of DNA
methylation in early embryonic development… CpG promoters have low DNA methylation levels …

DNA methylation profile of the mouse skeletal α-actin promoter during development and differentiation

PM Warnecke, SJ Clark - Molecular and cellular biology, 1999 - Taylor & Francis
… being extensively methylated and others sparsely methylated. Moreover… mouse does not
correlate with the methylation state of the promoter, as we find a similar low level of methylation

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… different developmental stages. In this Review, we discuss the mechanisms and functions
of DNA methylation and demethylation in both mice and humans at CpG-rich promoters, gene …

DNA methylation homeostasis in human and mouse development

M Iurlaro, F von Meyenn, W Reik - … opinion in genetics & development, 2017 - Elsevier
… role of DNA methylation when present at promoter or … DNA methylation and its oxidised
forms 5hmC and 5-formylcytosine (5fC) in gametes and early mouse embryos and by methylation

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes

CR Farthing, G Ficz, RK Ng, CF Chan, S Andrews… - PLoS …, 2008 - journals.plos.org
DNA methylation patterns are reprogrammed in primordial … and subsequent de novo
methylation. It has been suggested … genome-wide promoter analysis of DNA methylation in mouse

DNA methylation in mammalian development and disease

W Dean, D Lucifero, F Santos - … Research Part C: Embryo …, 2005 - Wiley Online Library
… from their viral promoters would result in … in early development and germ cell differentiation
in humans will influence our understanding of the potential impact of DNA methylation in …

DNA methylation reprogramming of functional elements during mammalian embryonic development

C Li, Y Fan, G Li, X Xu, J Duan, R Li, X Kang, X Ma… - Cell discovery, 2018 - nature.com
… We plotted the DNA methylation levels of promoters and genic regions for each … early mouse
embryogenesis 13 . Our data also showed that genes exhibiting hypomethylated promoters

DNA methylation: roles in mammalian development

ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
… Before exploring dynamic regulation within selected cellular systems, we provide a
breakdown of DNA methylation as it acts on promoters, repetitive elements and parent-specific …

Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… We establish that DNA methylation of CpG-island promoters is a primary and causal silencing
mechanism for restricting ectopic expression of a large panel of germline genes. While we …