DNA methylation of multiple promoter-associated CpG islands in adult acute lymphocytic leukemia
G Garcia-Manero, J Daniel, TL Smith, SM Kornblau… - Clinical cancer …, 2002 - AACR
… associations, we have analyzed the methylation status of 10 genes in … methylation of
multiple promoter-associated CpG islands is a common event in ALL, suggesting that methylation …
multiple promoter-associated CpG islands is a common event in ALL, suggesting that methylation …
[HTML][HTML] Patterns of DNMT1 promoter methylation in patients with acute lymphoblastic leukemia
T Rahmani, M Azad, B Chahardouli… - … journal of hematology …, 2017 - ncbi.nlm.nih.gov
… and biology of lymphoid malignancies, the detailed analysis of DNA methylation patterns
may be helpful for an explanation of the underlying regulatory mechanisms of the disease …
may be helpful for an explanation of the underlying regulatory mechanisms of the disease …
Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia
M Borssen, L Palmqvist, K Karrman, J Abrahamsson… - PloS one, 2013 - journals.plos.org
… less methylated cases [14]. Our knowledge about global promoter DNA methylation profiles
… In the present study we characterized the DNA methylation pattern in diagnostic pediatric T-…
… In the present study we characterized the DNA methylation pattern in diagnostic pediatric T-…
[HTML][HTML] Aberrant DNA methylation of key genes and Acute Lymphoblastic Leukemia
… The DNA methylation alterations in promoter regions of the … In leukemia, epigenetic silencing
by DNA methylation has been mostly reported in cyclin-dependent kinase inhibitors, DNA …
by DNA methylation has been mostly reported in cyclin-dependent kinase inhibitors, DNA …
Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia
… DNA hypomethylation was restricted to well-defined regions. Individual hyper- and … promoters
allowed discrimination of CLL samples from healthy controls. Promoter DNA methylation …
allowed discrimination of CLL samples from healthy controls. Promoter DNA methylation …
Enhancer DNA methylation in acute myeloid leukemia and myelodysplastic syndromes
L Benetatos, G Vartholomatos - Cellular and molecular life sciences, 2018 - Springer
… , and, in contrast to promoters, are not … promoters and DNA methylation has extensively
been studied, much less is known about the interplay between enhancers and DNA methylation…
been studied, much less is known about the interplay between enhancers and DNA methylation…
DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia
S Alvarez, J Suela, A Valencia, A Fernández… - PloS one, 2010 - journals.plos.org
… Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia
(… signatures with defined genomic rearrangements in acute myeloid leukemia are required. …
(… signatures with defined genomic rearrangements in acute myeloid leukemia are required. …
Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
WG Tong, WG Wierda, E Lin, SQ Kuang, BN Bekele… - Epigenetics, 2010 - Taylor & Francis
… /promoter microarray technique is a useful tool to study the genome-wide DNA methylation
profile in leukemia … of aberrant DNA methylation in patients with CLL that carry 17p deletion. …
profile in leukemia … of aberrant DNA methylation in patients with CLL that carry 17p deletion. …
The diagnostic value of DNA methylation in leukemia: a systematic review and meta-analysis
D Jiang, Q Hong, Y Shen, Y Xu, H Zhu, Y Li, C Xu… - PloS one, 2014 - journals.plos.org
… family that lacks DNA binding activity and has tumor suppressor function… Promoter of ID4
is consistently methylated to various degrees in CLL cells, and increased promoter methylation …
is consistently methylated to various degrees in CLL cells, and increased promoter methylation …
Gene-specific and global methylation patterns predict outcome in patients with acute myeloid leukemia
S Deneberg, M Grövdal, M Karimi, M Jansson, H Nahi… - Leukemia, 2010 - nature.com
… global DNA methylation as well as p15 promoter methylation … DNA methylation and
genome-wide promoter methylation. … low global DNA methylation levels paired with increased p15 …
genome-wide promoter methylation. … low global DNA methylation levels paired with increased p15 …
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