… , suggesting that repression of this sparsely methylated promoter was in fact mediated by a
… the effect of DNA methylation on transcription of CpG-deficient genes, using promoters of …

… methylation density and promoter strength are important parameters affecting the impact of
DNA methylation … requirement that methylation should be located near the promoter provides …

… Consequently, the strength of repression could depend on the local concentration of …
promoters in their regulation by DNA methylation. Therefore, we defined three classes of promoters …

… Numerous reports have shown the ability of promoter DNA methylation to inhibit
transcription of a wide variety of genes in in vitro transfection assays, and in some cases, such …

… Detailed studies of the effects of DNA methylation on promoter activity have revealed that
DNA methylation is a … strength: Evidence for involvement of a methyl-CpG binding protein. …

… As a measure of ‘promoter’ strength, luciferase activities were calculated from the intensity
of light produced as a consequence of beetle luciferin oxidation by firefly luciferase expressed …

… DNA methylation to transcription (eg, current evidence relating DNA methylation to imprinting),
as methylation … density of methyl-CpGs, and strength of the promoter. MeCPl molecules …

… The third and smallest group (7%) represents CGI promoters that are DNA methylated (filled
circles). There is no clear correlation between this group and any specific chromatin marks (…

… This can be accounted for by protection from DNA methylation through binding … DNA
methylation at promoters of inactive genes. Repression occurs when DNA methylation at promoter …

… level greater than 50% at the CpGs within -100 to +700 bp of the transcription start site (TSS),
we anticipated that a loss in DNA methylation in DKO1 cells at these promoters may reveal …