Maintenance and regulation of DNA methylation patterns in mammals

Z Chen, AD Riggs - Biochemistry and cell biology, 2005 - cdnsciencepub.com
… recent progress in understanding the regulation of mammalian DNA methylation patterns,
with an … methylation and discuss its implications for epigenetic fidelity and gene regulation. …

DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… In this review, we will discuss the basic function of DNA methylation in epigenetic gene
regulation, and further highlight its role in neural development and neurological disease. …

Regulation of DNA methylation by the Ras signaling pathway

AR MacLeod, J Rouleau, M Szyf - Journal of Biological Chemistry, 1995 - ASBMB
… We demonstrate that DNA methylation in an adrenocortical … in the level of DNA methylation,
DNA methyltransferase (MeTase) … in the levels of DNA methylation and DNA MeTase activity. …

DNA methylation

R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
regulation, DNA methylation and histone deacetylation, can be linked by MeCP-2.61,62
However, in some instances DNA methylation … the overall regulatory role of DNA methylation is …

DNA methylation and the regulation of gene transcription

JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
Methylation of DNA cytosine bases leads to the inaccessibility of DNA regulatory elements
… Our understanding of DNA methylation has advanced rapidly in recent years with the …

Ras regulation of DNA-methylation and cancer

SK Patra - Experimental cell research, 2008 - Elsevier
… , including DNA-methylation represent a fundamental regulatoryMethylated cytosine
residues of vertebrate DNA are … of DNA methyltransferase, DNMT1, for hemimethylated-DNA. …

Transcriptional regulation by DNA methylation

AR Poetsch, C Plass - Cancer treatment reviews, 2011 - Elsevier
… manner leading to a block of differentiation and proliferation either via biallelic mutation,
monoallelic mutation in combination with DNA methylation or DNA methylation on both alleles. …

The role of DNA methylation in gene regulation

PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
… The addition of a methyl group to a DNA base is known as DNA methylation. Typically, this
… as DNA methyltransferases. Importantly, DNA methylation is related to the regulation of gene …

Insulin gene expression is regulated by DNA methylation

A Kuroda, TA Rauch, I Todorov, HT Ku, IH Al-Abdullah… - PloS one, 2009 - journals.plos.org
DNA sequences that regulate transcription of the insulin gene and the majority of regulatory
… the role of DNA methylation in the regulation of mouse and human insulin gene expression. …

Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation

ED Nelson, ET Kavalali… - Journal of Neuroscience, 2008 - Soc Neuroscience
DNA methylation is an epigenetic mechanism that plays a critical role in the repression of
gene expression. Here, we show that DNA methyltransferase (DNMT) inhibition in …