Maintenance and regulation of DNA methylation patterns in mammals
… recent progress in understanding the regulation of mammalian DNA methylation patterns,
with an … methylation and discuss its implications for epigenetic fidelity and gene regulation. …
with an … methylation and discuss its implications for epigenetic fidelity and gene regulation. …
DNA methylation and its basic function
LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… In this review, we will discuss the basic function of DNA methylation in epigenetic gene
regulation, and further highlight its role in neural development and neurological disease. …
regulation, and further highlight its role in neural development and neurological disease. …
Regulation of DNA methylation by the Ras signaling pathway
AR MacLeod, J Rouleau, M Szyf - Journal of Biological Chemistry, 1995 - ASBMB
… We demonstrate that DNA methylation in an adrenocortical … in the level of DNA methylation,
DNA methyltransferase (MeTase) … in the levels of DNA methylation and DNA MeTase activity. …
DNA methyltransferase (MeTase) … in the levels of DNA methylation and DNA MeTase activity. …
DNA methylation
R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… regulation, DNA methylation and histone deacetylation, can be linked by MeCP-2.61,62
However, in some instances DNA methylation … the overall regulatory role of DNA methylation is …
However, in some instances DNA methylation … the overall regulatory role of DNA methylation is …
DNA methylation and the regulation of gene transcription
JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
… Methylation of DNA cytosine bases leads to the inaccessibility of DNA regulatory elements
… Our understanding of DNA methylation has advanced rapidly in recent years with the …
… Our understanding of DNA methylation has advanced rapidly in recent years with the …
Ras regulation of DNA-methylation and cancer
SK Patra - Experimental cell research, 2008 - Elsevier
… , including DNA-methylation represent a fundamental regulatory … Methylated cytosine
residues of vertebrate DNA are … of DNA methyltransferase, DNMT1, for hemimethylated-DNA. …
residues of vertebrate DNA are … of DNA methyltransferase, DNMT1, for hemimethylated-DNA. …
Transcriptional regulation by DNA methylation
AR Poetsch, C Plass - Cancer treatment reviews, 2011 - Elsevier
… manner leading to a block of differentiation and proliferation either via biallelic mutation,
monoallelic mutation in combination with DNA methylation or DNA methylation on both alleles. …
monoallelic mutation in combination with DNA methylation or DNA methylation on both alleles. …
The role of DNA methylation in gene regulation
PA Bommarito, RC Fry - Toxicoepigenetics, 2019 - Elsevier
… The addition of a methyl group to a DNA base is known as DNA methylation. Typically, this
… as DNA methyltransferases. Importantly, DNA methylation is related to the regulation of gene …
… as DNA methyltransferases. Importantly, DNA methylation is related to the regulation of gene …
Insulin gene expression is regulated by DNA methylation
… DNA sequences that regulate transcription of the insulin gene and the majority of regulatory
… the role of DNA methylation in the regulation of mouse and human insulin gene expression. …
… the role of DNA methylation in the regulation of mouse and human insulin gene expression. …
Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation
ED Nelson, ET Kavalali… - Journal of Neuroscience, 2008 - Soc Neuroscience
DNA methylation is an epigenetic mechanism that plays a critical role in the repression of
gene expression. Here, we show that DNA methyltransferase (DNMT) inhibition in …
gene expression. Here, we show that DNA methyltransferase (DNMT) inhibition in …
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