Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling
Background In recent years the Illumina HumanMethylation450 (HM450) BeadChip has
provided a user-friendly platform to profile DNA methylation in human samples. However …
provided a user-friendly platform to profile DNA methylation in human samples. However …
[HTML][HTML] Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip
Genome-wide analysis of DNA methylation has now become a relatively inexpensive
technique thanks to array-based methylation profiling technologies. The recently developed …
technique thanks to array-based methylation profiling technologies. The recently developed …
A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies
B Lehne, AW Drong, M Loh, W Zhang, WR Scott… - Genome biology, 2015 - Springer
DNA methylation plays a fundamental role in the regulation of the genome, but the optimal
strategy for analysis of genome-wide DNA methylation data remains to be determined. We …
strategy for analysis of genome-wide DNA methylation data remains to be determined. We …
missMethyl: an R package for analyzing data from Illumina's HumanMethylation450 platform
DNA methylation is one of the most commonly studied epigenetic modifications due to its
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …
role in both disease and development. The Illumina HumanMethylation450 BeadChip is a …
Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array
Abstract Background The Illumina HumanMethylation450 BeadChip (HM450K) measures
the DNA methylation of 485,512 CpGs in the human genome. The technology relies on …
the DNA methylation of 485,512 CpGs in the human genome. The technology relies on …
An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform
The proper identification of differentially methylated CpGs is central in most epigenetic
studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA …
studies. The Illumina HumanMethylation450 BeadChip is widely used to quantify DNA …
Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array
Background Measurement of genome-wide DNA methylation (DNAm) has become an
important avenue for investigating potential physiologically-relevant epigenetic changes …
important avenue for investigating potential physiologically-relevant epigenetic changes …
A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome Profiling
C Clark, P Palta, CJ Joyce, C Scott, E Grundberg… - PloS one, 2012 - journals.plos.org
DNA methylation is one of the most studied epigenetic marks in the human genome, with the
result that the desire to map the human methylome has driven the development of several …
result that the desire to map the human methylome has driven the development of several …
Validation of a DNA methylation microarray for 850,000 CpG sites of the human genome enriched in enhancer sequences
S Moran, C Arribas, M Esteller - Epigenomics, 2016 - Future Medicine
Aim: DNA methylation is the best known epigenetic mark. Cancer and other pathologies
show an altered DNA methylome. However, delivering complete DNA methylation maps is …
show an altered DNA methylome. However, delivering complete DNA methylation maps is …
[HTML][HTML] Analysis pipelines and packages for Infinium HumanMethylation450 BeadChip (450k) data
TJ Morris, S Beck - Methods, 2015 - Elsevier
Abstract The Illumina HumanMethylation450 BeadChip has become a popular platform for
interrogating DNA methylation in epigenome-wide association studies (EWAS) and related …
interrogating DNA methylation in epigenome-wide association studies (EWAS) and related …