Methylation in the human genome is known to be associated with development and disease.
The Illumina Infinium methylation arrays are by far the most common way to interrogate …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

Abstract The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-
throughput DNA methylation analysis. Several methods for normalization and processing of …

Background Modification of DNA by methylation of cytosines at CpG dinucleotides is a
widespread phenomenon that leads to changes in gene expression, thereby influencing and …

This study was originally conceived to test in a rigorous way the specificity of three major
approaches to high-throughput array-based DNA methylation analysis:(1) MeDIP, or …

Abstract Motivation: The recently released Infinium HumanMethylation450 array (the
'450k'array) provides a high-throughput assay to quantify DNA methylation (DNAm) at∼ 450 …

An abnormal pattern of DNA methylation occurs at specific genes in almost all neoplasms.
The lack of high-throughput methods with high specificity and sensitivity to detect changes in …

DNA methylation is one of the most commonly studied epigenetic marks, due to its role in
disease and development. Illumina methylation arrays have been extensively used to …

DNA methylation patterns are altered in numerous diseases and often correlate with
clinically relevant information such as disease subtypes, prognosis and drug response. With …

Hepatocellular carcinoma (HCC) incidence has increased in the US and also has one of the
fastest growing death rates of any cancer. The purpose of the current study was to discover …