DNA methylation data–based molecular subtype classification related to the prognosis of patients with cervical cancer

C Li, J Ke, J Liu, J Su - Journal of cellular biochemistry, 2020 - Wiley Online Library
Cervical cancer is one of the leading female health‐killers among all types of malignancies
globally. Human papillomavirus infection combined with genetic and epigenetic alterations …

Tumor DNA methylation profiles enable diagnosis, prognosis prediction, and screening for cervical cancer

J Tu, S Chen, S Wu, T Wu, R Fan… - International journal of …, 2022 - Taylor & Francis
Background DNA-methylation-based machine learning algorithms have demonstrated
powerful diagnostic capabilities, and these tools are currently emerging in many fields of …

A 5-gene DNA methylation signature is a promising prognostic biomarker for early-stage cervical cancer

H Chen, H Li, L Wang, Y Li, CY Yang - Journal of Obstetrics and …, 2022 - Taylor & Francis
The demographic information and overall survival (OS) of patients with cervical cancer
(CC)(pathological stage: IA–IIA) were extracted from the TCGA database. A univariate and …

A 10-gene prognostic methylation signature for stage I–III cervical cancer

S Cai, X Yu, Z Gu, Q Yang, B Wen, J Sheng… - Archives of Gynecology …, 2020 - Springer
Purpose Cervical cancer (CC) patients usually have poor prognosis. The present study aims
to find a DNA methylation signature for predicting survival of CC patients. Methods We …

HPV‐related methylation‐based reclassification and risk stratification of cervical cancer

S Yang, Y Wu, S Wang, P Xu, Y Deng… - Molecular …, 2020 - Wiley Online Library
Human papillomavirus (HPV) is a clear etiology of cervical cancer (CC). However, the
associations between HPV infection and DNA methylation have not been thoroughly …

A novel cervix carcinoma biomarker: pathological-epigenomics, integrated analysis of MethylMix algorithm and pathology for predicting response to cancer …

YC Yu, TM Shi, SL Gu, YH Li, XM Yang, Q Fan… - Frontiers in …, 2022 - frontiersin.org
Herein, A non-invasive pathomics approach was developed to reveal the methylation status
in patients with cervical squamous cell carcinoma and predict clinical outcomes and …

DNA methylation pattern in high-grade cervical intraepithelial neoplasia and cancer revealed by genomewide methylation analysis of cervical DNA

DA García, MC Abba, I Briceño… - Integrative Molecular …, 2017 - sedici.unlp.edu.ar
Cancer of the uterine cervix is caused by a subset of oncogenic human Papillomavirus
(HPV)-types with mucosal tropism. Besides the known effects of the viral oncoproteins on …

Aberrant gene-specific DNA methylation signature analysis in cervical cancer

S Bhat, SP Kabekkodu, VK Varghese… - Tumor …, 2017 - journals.sagepub.com
Multicomponent molecular modifications such as DNA methylation may offer sensitive and
specific cervical intraepithelial neoplasia and cervical cancer biomarkers. In this study, we …

Identification of tumor microenvironment and DNA methylation-related prognostic signature for predicting clinical outcomes and therapeutic responses in cervical …

B Liu, J Zhai, W Wang, T Liu, C Liu, X Zhu… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: Tumor microenvironment (TME) has been reported to have a strong
association with tumor progression and therapeutic outcome, and epigenetic modifications …

Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer

SA Farkas, N Milutin-Gašperov, M Grce, TK Nilsson - Epigenetics, 2013 - Taylor & Francis
The oncogenic human papilloma viruses (HPVs) are associated with precancerous cervical
lesions and development of cervical cancer. The DNA methylation signatures of the host …