Role of Epigenetics in Cancer and Targeted Therapies for Oncologic Treatments

M Srinivas, SP Sanjay, LP Manik… - Current Journal of …, 2024 - archive.bionaturalists.in
DNA sequence has little bearing on the dynamic and heritable changes to the genome that
occur in epigenetics. Both genetic and epigenetic alterations influence the development of …

[PDF][PDF] Role of epigenetic mechanisms in various cancer therapies

R Yadav, A Srivastava, S Chandra, AK Rai - … and Biological Evaluations, 2016 - core.ac.uk
Epigenetics play a role not just in the normal functioning of the cell and its development, but
also in diseases like neurological diseases and cancer. Epigenetic therapies can help to …

[HTML][HTML] Cancer treatment: an epigenetic view

C Aydin, R Kalkan - Global medical genetics, 2020 - thieme-connect.com
Cancer can be identified as an uncontrolled growth and reproduction of cell. Accumulation
of genetic aberrations (mutations of oncogenes and tumor-suppressor genes and epigenetic …

[图书][B] Epigenetic Advancements in Cancer

MK Mishra, KS Bishnupuri - 2016 - Springer
Recent biomedical advancement and discovery of unique epigenetic modifications to target
different cancer types has revolutionized the cancer treatment regime. In recent years, the …

Epigenetic alterations as a universal feature of cancer hallmarks and a promising target for personalized treatments

M Schnekenburger, C Florean, M Dicato… - Current topics in …, 2016 - ingentaconnect.com
Despite considerable scientific progress, the burden of cancer in our society remains a
major public health problem. Tumorigenesis is recognized as a complex and multistep …

[HTML][HTML] Epigenetic mechanisms as a new approach in cancer treatment: An updated review

M Fardi, S Solali, MF Hagh - Genes & diseases, 2018 - Elsevier
Epigenetic, along with genetic mechanisms, is essential for natural evolution and
maintenance of specific patterns of gene expression in mammalians. Global epigenetic …

Clinical Studies and Epi-Drugs in Various Cancer Types

TBE Cevik, Z Ozdemir, HB Erdem - Cancer Epigenetics - Springer
Cancer is characterized by modifications in the epigenetic mechanisms and chromatin
functions. Alterations in gene expression, as well as the development and progression of …

Clinical Studies and Epi-Drugs in Various Cancer Types

T Bahsi, E Cevik, Z Ozdemir, HB Erdem - Cancer Epigenetics, 2023 - Springer
Cancer is characterized by modifications in the epigenetic mechanisms and chromatin
functions. Alterations in gene expression, as well as the development and progression of …

[HTML][HTML] Cancer development, progression, and therapy: an epigenetic overview

S Sarkar, G Horn, K Moulton, A Oza, S Byler… - International journal of …, 2013 - mdpi.com
Carcinogenesis involves uncontrolled cell growth, which follows the activation of oncogenes
and/or the deactivation of tumor suppression genes. Metastasis requires down-regulation of …

The role of epigenetic regulation in cancer

J Zhang, C Yang, C Wu - Epigenetic Regulation in Overcoming …, 2021 - Elsevier
Cancer has always been one of the main threats to human health. Looking for its potential
pathogenic mechanism is a major challenge facing humanity. Epigenetic mechanisms are …