The basic physiology and pathophysiology of melatonin

B Claustrat, J Brun, G Chazot - Sleep medicine reviews, 2005 - Elsevier
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at
night under normal environmental conditions. The endogenous rhythm of secretion is …

Melatonin: Physiological effects in humans

B Claustrat, J Leston - Neurochirurgie, 2015 - Elsevier
Melatonin is a methoxyindole synthesized and secreted principally by the pineal gland at
night under normal light/dark conditions. The endogenous rhythm of secretion is generated …

Melatonin as a hormone: new physiological and clinical insights

J Cipolla-Neto, FG Amaral - Endocrine reviews, 2018 - academic.oup.com
Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

Melatonin and human rhythms

J Arendt - Chronobiology international, 2006 - Taylor & Francis
Melatonin signals time of day and time of year in mammals by virtue of its pattern of
secretion, which defines 'biological night.'It is supremely important for research on the …

The physiology and pharmacology of melatonin in humans

M Geoffriau, J Brun, G Chazot, B Claustrat - Hormone Research in …, 1998 - karger.com
Melatonin (MLT) is a methoxyindole secreted principally by the pineal gland. It is
synthesized at night under normal environmental conditions. The endogenous rhythm of …

Melatonin as a chronobiotic

J Arendt, DJ Skene - Sleep medicine reviews, 2005 - Elsevier
Melatonin, hormone of the pineal gland, is concerned with biological timing. It is secreted at
night in all species and in ourselves is thereby associated with sleep, lowered core body …

Melatonin: pharmacology, functions and therapeutic benefits

S Tordjman, S Chokron, R Delorme… - Current …, 2017 - ingentaconnect.com
Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal
gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of …

Melatonin: characteristics, concerns, and prospects

J Arendt - Journal of biological rhythms, 2005 - journals.sagepub.com
Melatonin is of great importance to the investigation of human biological rhythms. Its rhythm
in plasma or saliva provides the best available measure of the timing of the internal …

Basic aspects of melatonin action

DP Cardinali, P Pévet - Sleep medicine reviews, 1998 - Elsevier
Melatonin is synthesized and secreted during the dark period of the light-dark cycle. Thus,
melatonin has an obvious association with sleep, at least in diurnal animals. Rhythmic …

Melatonin in relation to physiology in adult humans: Mini Review

A Cagnacci - Journal of pineal research, 1996 - Wiley Online Library
The role exerted by melatonin in human physiology has not been completely ascertained.
Melatonin levels have been measured in different physiopathological conditions, but the …