Cytosine methylation is an epigenetically propagated DNA modification that can modify how
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …

DNA methylation occurs at cytosines, predominantly in the CpG dinucleotide context and is
a key epigenetic regulator of embryogenesis and stem-cell differentiation in mammals. The …

DNA methylation was the first epigenetic modification discovered. Until recently,
comprehensive coverage of the composition and distribution of methylated cytosines across …

Methylation of the cytosine base in DNA, DNA methylation, is an essential epigenetic mark
in mammals that contributes to the regulation of transcription. Several advances have been …

Methylation of cytosines can mediate epigenetic gene silencing and is the only known DNA
modification in eukaryotes. Recent efforts to map DNA methylation across mammalian …

From a fertilised egg to a mature organism, cells divide and accumulate epigenetic
information, which is faithfully passed on to daughter cells. DNA methylation consolidates …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

Methylation of cytosines in the mammalian genome represents a key epigenetic modification
and is dynamically regulated during development. Compelling evidence now suggests that …