While the field of epigenetics is increasingly recognized to contribute to the emergence of
phenotypes in mammalian research models across different developmental and …

Fig. 1 High levels of DNA methylation in gametes and early embryonic stages of zebrafish. a,
A Southern blot of DNA samples (100 ng) from sperm, adult tail and embryonic stages (2.2 h …

Highlights•Epigenetic information can be altered by environmental stressors.•The
mechanisms of epigenetic inheritance are complex and unclear.•DNA and histone …

The epigenome consists of chemical changes in DNA and chromatin that without modifying
the DNA sequence modulate gene expression and cellular phenotype. The epigenome is …

Background Exposure to environmental stressors during development may lead to latent
and transgenerational adverse health effects. To understand the role of DNA methylation in …

Background Zygotic genome activation (ZGA) occurs at the mid-blastula transition (MBT) in
zebrafish and is a period of extensive chromatin remodeling. Genome-scale gametic …

Parental environmental copper (Cu) exposure is widespread, causing problems for
sustainability of fish populations, and epigenetics is suggested to be fundamental during the …

DNA methylation, a well-studied epigenetic mark, is important for gene regulation in
adulthood and for development. Using genetic and epigenetic approaches, the present …

Epigenetic mechanisms traditionally have been studied in the domains of development and
disease, but they may also play important roles in ecological and evolutionary processes. In …

In natural fish populations, temperature increases can result in shifts in important phenotypic
traits. DNA methylation is an epigenetic mechanism mediating phenotypic changes …